Pesticides are chemical substances intended for preventing or controlling pests. These are toxic substances which contaminate soil, water bodies and vegetative crops. Excessive use of pesticides may cause destruction of biodiversity. In plants, pesticides lead to oxidative stress, inhibition of physiological and biochemical pathways, induce toxicity, impede photosynthesis and negatively affect yield of crops. Increased production of reactive oxygen species like superoxide radicals, O⁻₂ hydrogen peroxide, H₂O₂; singlet oxygen, O₂; hydroxyl radical, OH⁻; and hydroperoxyl radical HO₂₋, causes damage to protein, lipid, carbohydrate and DNA within plants. Plant growth regulators (PGR) are recognized for promoting growth and development under optimal as well as stress conditions. PGR combat adverse effect by acting as chemical messenger and under complex regulation, enable plants to survive under stress conditions. PGR mediate various physiological and biochemical responses, thereby reducing pesticide-induced toxicity. Exogenous applications of PGRs, such as brassinosteroid, cytokinins, salicylic acid, jasmonic acid, etc., mitigate pesticide toxicity by stimulating antioxidant defense system and render tolerance towards stress conditions. They provide resistance against pesticides by controlling production of reactive oxygen species, nutrient homeostasis, increase secondary metabolite production, and trigger antioxidant mechanisms. These phytohormones protect plants against oxidative damage by activating mitogen-stimulated protein kinase cascade. Current study is based on reported research work that has shown the effect of PGR in promoting plant growth subjected to pesticide stress. The present review covers the aspects of pesticidal response of plants and evaluates the contribution of PGRs in mitigating pesticide-induced stress and increasing the tolerance of plants. Further, the study suggests the use of PGRs as a tool in mitigating effects of pesticidal stress together with improved growth and development.

农药是用于预防或控制害虫的化学物质。这些有毒物质会污染土壤、水体和植物作物。过量使用农药可能会导致生物多样性遭到破坏。在植物中，农药会导致氧化应激、抑制生理生化途径、诱发毒性、阻碍光合作用并对作物产量产生负面影响。增加活性氧的产生，如超氧自由基、O ⁻ ₂过氧化氢、H ₂ O ₂ ；单线态氧，O ₂ ；羟基自由基， ^OH- ；和氢过氧自由基HO ₂₋ ，会对植物内的蛋白质、脂质、碳水化合物和DNA造成损害。植物生长调节剂 (PGR) 被认为可以在最佳条件和胁迫条件下促进生长和发育。 PGR通过充当化学信使并在复杂的调节下对抗不利影响，使植物能够在胁迫条件下生存。 PGR介导各种生理生化反应，从而降低农药引起的毒性。外源应用油菜素类固醇、细胞分裂素、水杨酸、茉莉酸等植物生长调节剂，通过刺激抗氧化防御系统减轻农药毒性，并赋予对应激条件的耐受性。它们通过控制活性氧的产生、营养稳态、增加次级代谢产物的产生并触发抗氧化机制来提供对杀虫剂的抵抗力。这些植物激素通过激活丝裂原刺激的蛋白激酶级联来保护植物免受氧化损伤。 目前的研究基于已报道的研究工作，该研究工作表明 PGR 在促进遭受农药胁迫的植物生长方面具有作用。本综述涵盖了植物农药反应的各个方面，并评估了植物生长调节剂在减轻农药引起的胁迫和提高植物耐受性方面的贡献。此外，该研究建议使用植物生长调节剂作为减轻农药胁迫影响以及改善生长和发育的工具。