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Validation of the ACS NSQIP Surgical Risk Calculator for Patients with Early Gastric Cancer Treated with Laparoscopic Gastrectomy
Journal of Gastric Cancer ( IF 3.2 ) Pub Date : 2020-01-01 , DOI: 10.5230/jgc.2020.20.e27
Saleh M Alzahrani 1 , Chang Seok Ko 1 , Moon-Won Yoo 1
Affiliation  

Purpose The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) risk calculator is useful in predicting postoperative adverse events. However, its accuracy in specific disorders is unclear. We validated the ACS NSQIP risk calculator in patients with gastric cancer undergoing curative laparoscopic surgery. Materials and Methods We included 207 consecutive early gastric cancer patients who underwent laparoscopic gastrectomy between January 2018 and January 2019. The preoperative characteristics and risks of the patients were reviewed and entered into the ACS NSQIP calculator. The estimated risks of postoperative outcomes were compared with the observed outcomes using C-statistics and Brier scores. Results Most of the patients underwent distal gastrectomy with Roux-en-Y reconstruction (74.4%). We did not observe any cases of mortality, venous thromboembolism, urinary tract infection, renal failure, or cardiac complications. The other outcomes assessed were complications such as pneumonia, surgical site infections, any complications requiring re-operation or hospital readmission, the rates of discharge to nursing homes/rehabilitation centers, and the length of stay. All C-statistics were <0 and the highest was for pneumonia (0.65; 95% confidence interval: 0.58–0.71). Brier scores ranged from 0.01 for pneumonia to 0.155 for other complications. Overall, the risk calculator was inconsistent in predicting the outcomes. Conclusions The ACS NSQIP surgical risk calculator showed low predictive ability for postoperative adverse events after laparoscopic gastrectomy for patients with early gastric cancer. Further research to adjust the risk calculator for these patients may improve its predictive ability.

中文翻译:

ACS NSQIP 手术风险计算器对接受腹腔镜胃切除术治疗的早期胃癌患者的验证

目的 美国外科医师学会国家手术质量改进计划 (ACS NSQIP) 风险计算器可用于预测术后不良事件。然而,它在特定疾病中的准确性尚不清楚。我们在接受根治性腹腔镜手术的胃癌患者中验证了 ACS NSQIP 风险计算器。材料与方法 我们纳入了 207 例在 2018 年 1 月至 2019 年 1 月期间连续接受腹腔镜胃切除术的早期胃癌患者。回顾了患者的术前特征和风险,并将其输入 ACS NSQIP 计算器。使用 C 统计量和 Brier 评分将术后结果的估计风险与观察到的结果进行比较。结果大部分患者接受了远端胃切除术并行Roux-en-Y重建(74.4%)。我们没有观察到任何死亡、静脉血栓栓塞、尿路感染、肾功能衰竭或心脏并发症的病例。评估的其他结果是并发症,如肺炎、手术部位感染、任何需要再次手术或再次住院的并发症、出院到疗养院/康复中心的比率以及住院时间。所有 C 统计量均 <0,最高的是肺炎(0.65;95% 置信区间:0.58-0.71)。Brier 评分范围从肺炎的 0.01 到其他并发症的 0.155。总体而言,风险计算器在预测结果方面不一致。结论 ACS NSQIP 手术风险计算器对早期胃癌患者腹腔镜胃切除术后不良事件的预测能力较低。
更新日期:2020-01-01
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