Background Intravenous recombinant tissue plasminogen activator is the only golden approved medical therapy for acute ischemic stroke, guidelines for its injection relay on reducing or preventing associated hemorrhage as a side effect, yet hemorrhage is not the only possible complication, further embolization following injection is also a possibility; in this case report, peripheral embolization following intravenous recombinant tissue plasminogen activator with two possible explanations one related to the treatment and another related to the patient liability is represented. Case presentation A 78-year-old male presenting with acute onset of stroke, received intravenous recombinant tissue plasminogen activator, 16 h later he developed acute limb ischemia. Conclusion Peripheral embolization may happen within hours from intravenous recombinant tissue plasminogen activator administration.

中文翻译：

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急性缺血性脑卒中溶栓后外周栓塞一例

背景 静脉重组组织纤溶酶原激活剂是唯一获批的急性缺血性中风药物治疗，其注射指南以减少或预防相关出血为副作用，但出血不是唯一可能的并发症，注射后进一步栓塞也是可能性; 在本病例报告中，描述了静脉注射重组组织纤溶酶原激活剂后的外周栓塞，有两种可能的解释，一种与治疗有关，另一种与患者的责任有关。病例介绍 一名 78 岁男性，急性中风发作，静脉注射重组组织纤溶酶原激活剂，16 小时后出现急性肢体缺血。