当前位置: X-MOL 学术BMC Bioinform. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
BMC Bioinformatics ( IF 2.9 ) Pub Date : 2020-10-07 , DOI: 10.1186/s12859-020-03790-1
Liang-Rui Ren , Ying-Lian Gao , Jin-Xing Liu , Junliang Shang , Chun-Hou Zheng

As a machine learning method with high performance and excellent generalization ability, extreme learning machine (ELM) is gaining popularity in various studies. Various ELM-based methods for different fields have been proposed. However, the robustness to noise and outliers is always the main problem affecting the performance of ELM. In this paper, an integrated method named correntropy induced loss based sparse robust graph regularized extreme learning machine (CSRGELM) is proposed. The introduction of correntropy induced loss improves the robustness of ELM and weakens the negative effects of noise and outliers. By using the L2,1-norm to constrain the output weight matrix, we tend to obtain a sparse output weight matrix to construct a simpler single hidden layer feedforward neural network model. By introducing the graph regularization to preserve the local structural information of the data, the classification performance of the new method is further improved. Besides, we design an iterative optimization method based on the idea of half quadratic optimization to solve the non-convex problem of CSRGELM. The classification results on the benchmark dataset show that CSRGELM can obtain better classification results compared with other methods. More importantly, we also apply the new method to the classification problems of cancer samples and get a good classification effect.

中文翻译:

基于熵诱导损失的稀疏鲁棒图正则化极限学习机,用于癌症分类

作为一种具有高性能和出色的泛化能力的机器学习方法,极限学习机(ELM)在各种研究中越来越受欢迎。已经提出了针对不同领域的各种基于ELM的方法。但是,对噪声和异常值的鲁棒性始终是影响ELM性能的主要问题。本文提出了一种基于熵诱导损失的稀疏鲁棒图正则化极限学习机(CSRGELM)的集成方法。引入介电常数引起的损耗提高了ELM的鲁棒性,并减弱了噪声和异常值的负面影响。通过使用L2,1-范数约束输出权重矩阵,我们倾向于获得稀疏的输出权重矩阵,以构建更简单的单隐藏层前馈神经网络模型。通过引入图正则化来保留数据的局部结构信息,新方法的分类性能得到了进一步提高。此外,我们设计了一种基于半二次优化思想的迭代优化方法,以解决CSRGELM的非凸问题。基准数据集上的分类结果表明,与其他方法相比,CSRGELM可以获得更好的分类结果。更重要的是,我们还将新方法应用于癌症样本的分类问题,并取得了良好的分类效果。基准数据集上的分类结果表明,与其他方法相比,CSRGELM可以获得更好的分类结果。更重要的是,我们还将新方法应用于癌症样本的分类问题,并取得了良好的分类效果。基准数据集上的分类结果表明,与其他方法相比,CSRGELM可以获得更好的分类结果。更重要的是,我们还将新方法应用于癌症样本的分类问题,并取得了良好的分类效果。
更新日期:2020-10-08
down
wechat
bug