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Influence of the Medial Malleolus Osteotomy on the Clinical Outcome of M-BMS + I/III Collagen Scaffold in Medial Talar Osteochondral Lesion (German Cartilage Register/Knorpelregister DGOU)
CARTILAGE ( IF 2.8 ) Pub Date : 2020-10-08 , DOI: 10.1177/1947603520961169
Oliver Gottschalk 1, 2 , Sebastian Felix Baumbach 1, 2 , Sebastian Altenberger 3 , Daniel Körner 4 , Matthias Aurich 5 , Christian Plaass 6 , Sarah Ettinger 6 , Daniel Guenther 7 , Christoph Becher 8 , Hubert Hörterer 1, 2 , Markus Walther 1
Affiliation  

Objective

Osteochondral lesions of the talus are common injuries, with one of the leading treatment options being the M-BMS (matrix-augmented bone marrow stimulation) + I/III collagen scaffold. Osteotomy of the medial malleolus is not unusual but presents the risk of malunion or irritation by hardware. The aim of the study was to analyze data from the German Cartilage Society (Knorpelregister DGOU) to evaluate the influence of medial malleolar osteotomy on clinical results of M-BMS + I/III collagen scaffold.

Design

The ankle module of the Cartilage Register includes a total of 718 patients, while 45 patients met the inclusion criteria. Patients were treated with an M-BMS + I/III collagen scaffold of the medial talus, 30 without and 15 with an osteotomy of the medial malleolus. The follow-up evaluations included FAAM (Foot and Ankle Ability Measure), FAOS (Foot and Ankle Outcome Score), and VAS (visual analogue scale).

Results

Forty-five patients (22 male, 23 female) aged between 18 and 69 years (mean: 34 years) were included in this study. Between preoperative and 12 months postoperative, we noted a significant improvement in FAAM-ADL (Activity of Daily Living) (P = 0.004) as well as FAOS-Pain (P = 0.001), FAOS-Stiffness (P = 0.047), FAOS-ADL (P = 0.002), FAOS-Sport (P = 0.001), and FAOS Quality of Life (P = 0.009). There was no significant difference between patients who underwent an osteotomy or not.

Conclusion

The results show a significant improvement in patients’ outcome scores following a M-BMS + I/III collagen scaffold. No statistical difference was noted among those undergoing medial malleolar osteotomy.



中文翻译:

内踝截骨术对内侧距骨骨软骨病变中 M-BMS + I/III 胶原支架临床结果的影响(德国软骨注册/Knorpelregister DGOU)

客观的

距骨的骨软骨损伤是常见的损伤,主要的治疗选择之一是 M-BMS(基质增强骨髓刺激)+ I/III 胶原支架。内踝截骨术并不罕见,但存在畸形愈合或硬件刺激的风险。该研究的目的是分析来自德国软骨学会 (Knorpelregister DGOU) 的数据,以评估内踝截骨术对 M-BMS + I/III 胶原支架临床结果的影响。

设计

Cartilage Register 的踝关节模块共包括 718 名患者,其中 45 名患者符合纳入标准。患者接受了内侧距骨的 M-BMS + I/III 胶原支架治疗,其中 30 名没有内踝截骨术,15 名患者接受了内踝截骨术。后续评估包括FAAM(足踝能力测量)、FAOS(足踝结果评分)和VAS(视觉模拟量表)。

结果

本研究纳入了 45 名年龄在 18 至 69 岁(平均:34 岁)之间的患者(22 名男性,23 名女性)。在术前和术后 12 个月之间,我们注意到 FAAM-ADL(日常生活活动)(P = 0.004)以及FAOS-疼痛(P = 0.001)、FAOS-刚度(P = 0.047)、FAOS- ADL ( P = 0.002)、FAOS-Sport ( P = 0.001) 和 FAOS 生活质量 ( P = 0.009)。接受或不接受截骨术的患者之间没有显着差异。

结论

结果显示,在使用 M-BMS + I/III 胶原支架后,患者的预后评分显着提高。接受内踝截骨术的患者无统计学差异。

更新日期:2020-10-08
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