Environmental perfluoroalkyl substance (PFAS) concentrations have increased in the last decades, although their behaviour in the environment and potential deleterious effects are still unclear. In this context, the present study aimed to assess potential associations among these compounds in three fish species from differentially contaminated areas in southeastern Brazil, and morphometric indices used to assess environmental exposure effects, Fulton’s condition factor (FCF), the Hepatossomatic index (HSI) and the weight to length scaling coefficient (SC). Fish samples were collected from three differentially contaminated study areas in the state of Rio de Janeiro, Brazil, Guanabara Bay (GB), the Paraíba do Sul River (PS) and the Rodrigo de Freitas Lagoon (RFL). Silver scabbardfish (Lepidopus caudatus) and whitemouth croaker (Micropogonias furnieri) were sampled from both the PS (N=5 scabbardfish and N=9 croaker) and GB (N=10 for both species), while mullet (Mugil liza) were sampled from GB (N=15) and RFL (N=10). Results indicate that some of the morphometric indices seem to be directly affected by PFAS contaminant trends. Significant differences (p<0.05) among FCF were observed for mullet and croaker, while significant HSI differences (p<0.05) were observed only for croaker. The SC for each fish population varied among sampling site and fish population and did not seem to follow a fixed trend, corroborating previous assessments. A discriminant canonical analysis demonstrated higher discriminating contributions for the FCF and two PFAS, namely PFDA and PFOA. This variation is probably due to differential PFAS accumulation reflecting differences in trophic levels, although no direct associations between individual PFAS and the assessed morphometric indices were noted. PFAS, however, comprise several compounds, and each may be a different contributor to deleterious physiological effects. Further assessments are required, to better understand the potential deleterious effects of these compounds on populational fish health status.

在过去的几十年中，环境全氟烷基物质（PFAS）的浓度有所增加，尽管其在环境中的行为和潜在的有害影响仍不清楚。在此背景下，本研究旨在评估巴西东南部受不同污染地区的三种鱼类中这些化合物之间的潜在关联，以及用于评估环境暴露影响的形态计量指数，富尔顿条件因子（FCF），肝体指数（HSI）以及权重长度缩放系数（SC）。从巴西里约热内卢州，瓜纳巴拉湾（GB），南帕拉伊巴杜苏河（PS）和罗德里戈·德·弗雷塔斯泻湖（RFL）的三个受不同污染的研究区域收集了鱼类样品。银sc鱼（Lepidopus caudatus）和白嘴鱼（Micropogonias furnieri）分别从PS（N = 5 abb鱼和N = 9 croaker）和GB（两种鱼N = 10）中取样，而鱼（Mugil liza）分别来自GB（N = 15）和RFL（N = 10）。结果表明，某些形态指标似乎直接受到PFAS污染物趋势的影响。鱼和黄鱼在FCF之间观察到显着差异（p <0.05），而仅黄鱼在FCI之间观察到显着的HSI差异（p <0.05）。每个鱼类种群的标准偏差在采样地点和鱼类种群之间有所不同，并且似乎没有遵循固定的趋势，从而证实了先前的评估。判别标准分析表明，对FCF和两种PFAS（即PFDA和PFOA）的贡献较高。这种变化可能是由于PFAS累积差异所致，反映了营养水平的差异，尽管未注意到各个PFAS与评估形态指标之间的直接关联。PFAS，但是，包含几种化合物，并且每种可能是有害生理作用的不同贡献者。需要进一步评估，以更好地了解这些化合物对鱼类种群健康状况的潜在有害影响。