The simply prepared CuMgAl hydrotalcite (CuMgAl-LDH) has been developed as an efficient catalyst for the aerobic oxidation of ethylbenzene to acetophenone in the presence of N-Hydroxyphthalimide (NHPI). Various alkyl arenes could be tolerated under the selected reaction conditions. The kinetic study showed that the oxidation of ethylbenzene is a first-order reaction over CuMgAl-LDH. The mechanism study indicated that CuMgAl-LDH could accelerate not only the conversion of ethylbenzene, but also the transformation of the alcohol intermediate to ketone. The positive effect of surface basicity of the catalyst on the reaction has been observed in the aerobic oxidation of the ethylbenzene.

已开发出简单制备的CuMgAl水滑石（CuMgAl-LDH）作为在N-羟基邻苯二甲酰亚胺（NHPI）存在下将乙苯有氧氧化为苯乙酮的有效催化剂。在选定的反应条件下可以耐受各种烷基芳烃。动力学研究表明乙苯的氧化是CuMgAl-LDH上的一级反应。机理研究表明，CuMgAl-LDH不仅可以促进乙苯的转化，而且可以促进醇中间体向酮的转化。在乙苯的好氧氧化中已经观察到催化剂的表面碱性对反应的积极影响。