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A discussion on the potential impact of residential radon exposure on the quality of exposure and risk assessment for former uranium miners
Radiation and Environmental Biophysics ( IF 1.7 ) Pub Date : 2020-10-08 , DOI: 10.1007/s00411-020-00875-6
Jing Chen 1
Affiliation  

Epidemiological evidence of lung cancer risk from radon is based mainly on studies of underground miners where occupational exposures were, historically, relatively high in comparison to residential indoor exposure. However, radiation protection measures have caused radon levels in uranium mines to decrease significantly in more recent periods. Miners’ occupational exposure is limited to their working years while they are exposed to environmental radon at home over their entire lifetime. Even during their limited working years, workers spend much more time at home than in workplaces. The biological effect of radon in mines cannot be distinguished from the biological effect of residential radon. Therefore, for an exposure–risk relationship study of former uranium miners, excess radon-induced lung cancer cases should be related to the combined radon exposure cumulated in workplaces and at homes in excess of the radon exposure of the reference population. This is especially important when residential radon levels differ or vary significantly between miners and the reference population over the course of extended follow-up years. This paper reviews some recent studies on former uranium miners, shares what seems controversial to the author and wonders whether lifetime exposure at home to widely varying radon concentrations can actually impact the quality of exposure assessment, and hence impact the results of the exposure–risk relationship.



中文翻译:

讨论住宅ra暴露对前铀矿工暴露质量和风险评估的潜在影响

ra引起的肺癌风险的流行病学证据主要是基于对地下矿工的研究,从历史上看,与居民室内暴露相比,职业暴露相对较高。但是,辐射防护措施已导致铀矿中的ra水平在最近时期显着下降。矿工的职业暴露限于他们的工作年限,而他们一生中都在家中遭受环境ra的侵害。即使在有限的工作年中,工人在家里花费的时间也比在工作场所花费的时间多得多。mine在矿井中的生物效应无法与居民用ra的生物效应区分开。因此,对于前铀矿工的暴露-风险关系研究,ra引起的肺癌过多病例应与工作场所和家庭中累计的exposure暴露总量超过参考人群的exposure暴露有关。当矿工与参考人群之间在长期随访期间居民residential水平不同或有显着差异时,这一点尤其重要。本文回顾了一些有关前铀矿工的最新研究,分享了作者颇有争议的观点,并想知道在家中终生暴露于广泛的varying浓度是否会真正影响暴露评估的质量,从而影响暴露-风险关系的结果。 。当矿工与参考人群之间在长期随访期间居民residential水平不同或有显着差异时,这一点尤其重要。本文回顾了一些有关前铀矿工的最新研究,分享了作者颇有争议的观点,并想知道在家中终生暴露于广泛的varying浓度是否会真正影响暴露评估的质量,从而影响暴露-风险关系的结果。 。当矿工与参考人群之间在长期随访期间居民residential水平不同或有显着差异时,这一点尤其重要。本文回顾了一些有关前铀矿工的最新研究,分享了作者颇有争议的观点,并想知道在家中终生暴露于广泛的varying浓度是否会真正影响暴露评估的质量,从而影响暴露-风险关系的结果。 。

更新日期:2020-10-08
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