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Diagnostic approaches and contribution of next-generation sequencing technologies in genomic investigation of Vibrio parahaemolyticus that caused acute hepatopancreatic necrosis disease (AHPND)
Aquaculture International ( IF 2.2 ) Pub Date : 2020-09-26 , DOI: 10.1007/s10499-020-00610-4
Lean Huat Yu 1 , Cindy Shuan Ju Teh 2 , Kien Pong Yap 1 , Kwai Lin Thong 3
Affiliation  

A unique strain of Vibrio parahaemolyticus (designated as VPAHPND) causes acute hepatopancreatic necrosis disease (AHPND), a deadly bacterial disease associated with mass mortality in cultured shrimps since 2009. AHPND is responsible for severe economic losses worldwide, causing multimillion-dollar loss annually. Because of the rapid and high mortality rates in shrimps, substantial research has been carried out to develop rapid detection techniques. Also, recent technological advances such as the next-generation sequencing (NGS) have made it possible to elucidate relevant information about a pathogen in a single assay. This review summarizes the current research pertaining to VPAHPND, focusing on diagnosis and contribution of NGS technologies in the genomic studies of AHPND.



中文翻译:

下一代测序技术在引起急性肝胰腺坏死病 (AHPND) 的副溶血性弧菌基因组研究中的诊断方法和贡献

一种独特的副溶血性弧菌菌株(指定为 VP AHPND)导致急性肝胰腺坏死病(AHPND),这是一种致命的细菌性疾病,自 2009 年以来与养殖虾的大量死亡有关。AHPND 造成全球严重的经济损失,每年造成数百万美元的损失. 由于虾的快速和高死亡率,已经进行了大量研究以开发快速检测技术。此外,最近的技术进步,如下一代测序 (NGS),使得在一次检测中阐明有关病原体的相关信息成为可能。本综述总结了与 VP AHPND相关的当前研究, 专注于 NGS 技术在 AHPND 基因组研究中的诊断和贡献。

更新日期:2020-10-08
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