In this work, one-step fabrication of electrochemical reduced graphene oxide-carboxyl functionalized multi-walled carbon nanotubes (ErGO-[Formula: see text]MWCNTs) was successfully presented using potentiostatic method (PM). Characteristics of nanocomposite film were studied by using scanning electron microscopic (SEM) and electrochemical experiments. Furthermore, nanocomposite film of ErGO-[Formula: see text]MWCNTs was presented to develop a sensitive voltammetric sensor for detection of clopidogrel bisulphate (CLP). Electrochemical tests showed that nanocomposite film of ErGO-[Formula: see text]MWCNTs modified electrode can effectively increase currents to the oxidation of CLP due to the large accessible surface area as well as its excellent conductivity. Under optimum conditions, response peak currents were linear related to CLP in the range of [Formula: see text] to [Formula: see text] with a lower detection limits of [Formula: see text] ([Formula: see text]). Moreover, the proposed method exhibited an excellent selectivity, stability, reproducibility and was applied successfully for determination of CLP content in tablet dosage form with acceptable recovery values.

中文翻译：

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电化学还原氧化石墨烯-羧基功能化多壁碳纳米管薄膜的一步制备及其作为测定硫酸氢氯吡格雷的平台

在这项工作中，使用恒电位法 (PM) 成功地提出了电化学还原氧化石墨烯-羧基官能化多壁碳纳米管 (ErGO-[公式：见正文]MWCNTs) 的一步制备。采用扫描电子显微镜（SEM）和电化学实验研究了纳米复合薄膜的特性。此外，提出了 ErGO-[公式：见正文]MWCNTs 的纳米复合膜，以开发用于检测硫酸氢氯吡格雷 (CLP) 的灵敏伏安传感器。电化学测试表明，ErGO-[分子式：见正文]MWCNTs修饰电极的纳米复合膜由于具有较大的可及表面积和优异的导电性，可以有效增加CLP氧化的电流。在最佳条件下，响应峰值电流在 [公式：参见文本] 到 [公式：参见文本] 的范围内与 CLP 呈线性相关，检测限为 [公式：参见文本]（[公式：参见文本]）。此外，所提出的方法表现出优异的选择性、稳定性、重现性，并成功地应用于片剂中 CLP 含量的测定，具有可接受的回收率值。