The appearance of excessive inflammatory activity is associated with onset of many disease states. Such non-productive responses are often the basis of the mortality consequent to incurring numerous disorders. The current outbreak of coronavirus disease 2019 caused by the virus “severe acute respiratory syndrome coronavirus 2” is a striking reflection of the inadequacy of current medical science to adequately address this issue. The usefulness of a range of materials of botanical origin in the attenuation of both chronic and acute inflammatory responses to various disease stressors is described. The properties of preparations of plant-based origin often parallel those of synthesized pharmacologics, but differ from them in some key respects. These differences can lead to more traditional preparations having distinct therapeutic advantages but also a number of specific shortcomings. The strengths and weaknesses of these materials are objectively contrasted with that of a more orthodox pharmacological approach. Each of these emphases in style has specific advantages and they should not be considered as competitors, but rather as accomplices in combating adverse states involving derangement of immune function.

Impact statement

A large component of many disease states is the improper regulation of immune function. This commonly leads to the appearance of redundant inflammation which does not effectively address any underlying issue but actually impedes a successful response to disease-induced metabolic derangement. There is currently no means of successfully addressing this problem which is especially relevant in the ongoing viral pandemic of SARS-CoV-2. In view of this failure, new courses of action need to be contemplated. This review proposes reconsideration of the potential utility of natural compounds originating from plants in order to address this deficit. Such a new direction, in concert with more conventional strategies could help to alleviate this wide-ranging crisis.

中文翻译：

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使用植物提取物减轻急性和慢性炎症

过度炎症活动的出现与许多疾病状态的发生有关。这种非生产性反应常常是导致多种疾病导致死亡的基础。当前由“严重急性呼吸综合征冠状病毒2”病毒引起的2019冠状病毒病的爆发，引人注目地反映出当前医学科学不足以充分解决这一问题。描述了一系列植物来源的材料在减弱对各种疾病应激源的慢性和急性炎症反应中的用途。植物来源制剂的特性通常与合成药理学的特性相似，但在一些关键方面与它们不同。这些差异可能导致更传统的制剂具有明显的治疗优势，但也存在许多具体的缺点。这些材料的优点和缺点与更正统的药理学方法进行客观对比。这些风格上的每一个重点都有特定的优势，它们不应被视为竞争对手，而应被视为对抗涉及免疫功能紊乱的不利状态的共犯。

影响报告

许多疾病状态的一个重要组成部分是免疫功能的不当调节。这通常会导致多余炎症的出现，这种炎症不能有效解决任何潜在问题，实际上会阻碍对疾病引起的代谢紊乱的成功反应。目前尚无成功解决这一问题的方法，该问题与正在进行的 SARS-CoV-2 病毒大流行尤其相关。鉴于这一失败，需要考虑新的行动方针。本综述建议重新考虑源自植物的天然化合物的潜在效用，以解决这一缺陷。这样的新方向与更传统的战略相结合可能有助于缓解这场广泛的危机。