Since the emergence of MRSA in the 1960s, a gradual increase in infections by resistant bacteria has been observed. Clinical manifestations may vary from brand to critical condition due to host risk factors, as well as pathogen virulence and resistance. The high adaptability and pathogenic profile of MRSA clones contributed to its spread in hospital and community settings. In Brazil, the first MRSA isolates were reported in the late 1980s, and since then different genetic profiles, such as the Brazilian epidemic clone (BEC) and other clones considered a pandemic, became endemic in the Brazilian population. Additionally, Brazil’s MRSA clones were shown to be able to transfer genes involved in multidrug resistance and enhanced pathogenic properties. These events contributed to the rise of highly resistant and pathogenic MRSA. In this review, we present the main events which compose the history of MRSA in Brazil, including numbers and locations of isolation, as well as types of staphylococcal cassette chromosome mec (SCCmec) found in the Brazilian territory.

中文翻译：

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巴西耐甲氧西林金黄色葡萄球菌的历史

自1960年代MRSA出现以来，已观察到耐药菌感染的数量逐渐增加。由于宿主的危险因素以及病原体的毒力和耐药性，临床表现可能会因品牌和危急状况而异。MRSA克隆的高适应性和致病性特征有助于其在医院和社区中的传播。在巴西，最早的MRSA分离株是在1980年代末报告的，此后，不同的遗传特征（例如巴西流行性克隆（BEC）和其他被认为是大流行的克隆）在巴西人口中流行。此外，巴西的MRSA克隆被证明能够转移涉及多药耐药性和增强的致病性的基因。这些事件促进了高抗性和致病性MRSA的兴起。在这篇评论中mec（SCC mec）在巴西境内发现。