Abstract The chemical constituents and antimicrobial activity of hydro distilled essential oil from the stem of Magnolia coco (Lour.) DC. were reported. The constituents of the essential oil were determined using gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC/MS) while the antimicrobial action was evaluated by using microdilution broth susceptibility assay. The major com- pounds in the essential oil were sabinene (31.9 %) and β-pinene (11.8 %). The antimicrobial study depicted by minimum inhibitory concentration (MIC) showed that the essential oil was active against Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 14579 and Candida albicans ATCC 10231 with MIC value of 16.0 μg/mL as well as Enterococcus faecalis ATCC 299212 and Pseudomonas aeruginosa ATCC 27853 with MIC value of 32.0 μg/mL. The obtained IC50 values of the antimicrobial efficacy were 7.89, 7.66, 8.33, 16.44, and 15.67 μg/mL respectively. This report, the first of its kind, indicates the potential of M. coco stem essential oil as a source of anti-microbial principle.

中文翻译：

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来自 Magnolia coco (Lour.) DC 茎精油的化学成分和抗菌活性。来自越南

摘要 来自 Magnolia coco (Lour.) DC 茎的水蒸馏精油的化学成分和抗菌活性。被举报。使用气相色谱-火焰离子化检测器 (GC-FID) 和气相色谱-质谱 (GC/MS) 测定精油的成分，而使用微量稀释肉汤敏感性测定评估抗菌作用。精油中的主要化合物是桧烯 (31.9 %) 和 β-蒎烯 (11.8 %)。以最低抑菌浓度 (MIC) 表示的抗菌研究表明，该精油对金黄色葡萄球菌 ATCC 25923、蜡状芽孢杆菌 ATCC 14579 和白色念珠菌 ATCC 10231 具有活性，MIC 值为 16.0 μg/mL 以及粪肠球菌 ATCC212seuseus 299铜绿假单胞菌 ATCC 27853，MIC 值为 32.0 μg/mL。获得的抗微生物功效的 IC50 值分别为 7.89、7.66、8.33、16.44 和 15.67 μg/mL。这份报告是同类报告中的第一个，表明 M. coco 茎精油作为抗微生物原理的来源的潜力。