Herein, one‐pot synthesis of pyrimido[4,5‐b]quinoline and indenopyrido[2,3‐d]pyrimidine derivatives was developed by the three‐component reaction of aldehydes, 6‐amino‐1,3‐dimethyluracil, and 1,3‐dicarbonyl compounds in the presence of glycolic acid‐supported cobalt ferrite CoFe₂O₄@SiO₂@Si (CH₂)₃NHCOOCH₂COOH as a novel magnetic catalyst in ethanol at reflux conditions. Glycolic acid‐supported cobalt ferrite was characterized via Fourier transform infrared spectroscopy (FT‐IR), X‐ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy‐dispersive X‐ray spectroscopy (EDX), and vibrating sample magnetometer (VSM). Moreover, the catalyst was easily recovered with magnetic separation and recycled at least for five times without significant loss of its catalytic activity. The products were formed in excellent yields over appropriate reaction times under environmentally friendly conditions. The high efficiency and easy isolation of catalyst from products with an external permanent magnet are some of the remarkable advantages of this method.

中文翻译：

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乙醇酸负载的钴铁氧体催化嘧啶[4,5-b]喹啉和茚并吡啶并[2,3-d]嘧啶衍生物的一锅法合成

在此，通过醛，6-氨基-1,3-二甲基尿嘧啶和1的三组分反应开发了嘧啶[4,5- b ]喹啉和茚并吡啶并[2,3- d ]嘧啶衍生物的一锅法合成方法。乙醇酸负载的钴铁氧体CoFe ₂ O ₄ @SiO ₂ @Si（CH ₂）₃ NHCOOCH ₂存在下的，3-二羰基化合物COOH作为新型的磁性催化剂在乙醇中回流条件下。乙醇酸负载的钴铁氧体通过傅里叶变换红外光谱（FT-IR），X射线衍射（XRD），热重分析（TGA），扫描电子显微镜（SEM），透射电子显微镜（TEM），能量分散法进行了表征X射线光谱（EDX）和振动样品磁力计（VSM）。而且，该催化剂易于通过磁分离回收，并且至少循环了五次而没有明显丧失其催化活性。在环境友好的条件下，在适当的反应时间内，以极高的收率形成产物。该方法的高效和易于从带有外部永磁体的产品中分离出来的催化剂是该方法的显着优势。