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Glycogen Metabolism: IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway (Adv. Sci. 19/2020)
Advanced Science ( IF 14.3 ) Pub Date : 2020-10-07 , DOI: 10.1002/advs.202070108
Xiaopeng Zhu , Ting Yao , Ru Wang , Shanshan Guo , Xin Wang , Zhenqi Zhou , Yan Zhang , Xiaozhen Zhuo , Ruitao Wang , John Zhong Li , Tiemin Liu , Xingxing Kong

Little is known about how glycogen metabolism is manipulated during exercise. In article number 2001502, John Zhong Li, Tiemin Liu, Xingxing Kong, and coworkers identify that interferon regulatory factor 4 (IRF4) in skeletal muscle regulates glycogen metabolism and subsequent exercise capacity. This work reveals a regulatory pathway including IRF4/protein targeting to glycogen (PTG)/glycogen synthesis on controlling exercise capacity.
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中文翻译:

糖原代谢:骨骼肌中的IRF4通过PTG /糖原途径调节运动能力(Adv。Sci。19/2020)

关于运动过程中糖原代谢的操纵机制知之甚少。在文章2001502中,John Zhong Li,Tiemin Liu,Kingxing Kong和他的同事们发现骨骼肌中的干扰素调节因子4(IRF4)调节糖原代谢和随后的运动能力。这项工作揭示了一种调控途径,包括在控制运动能力上将IRF4 /蛋白质靶向糖原(PTG)/糖原合成。
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更新日期:2020-10-07
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