Little is known about how glycogen metabolism is manipulated during exercise. In article number 2001502, John Zhong Li, Tiemin Liu, Xingxing Kong, and coworkers identify that interferon regulatory factor 4 (IRF4) in skeletal muscle regulates glycogen metabolism and subsequent exercise capacity. This work reveals a regulatory pathway including IRF4/protein targeting to glycogen (PTG)/glycogen synthesis on controlling exercise capacity.

中文翻译：

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糖原代谢：骨骼肌中的IRF4通过PTG /糖原途径调节运动能力（Adv。Sci。19/2020）

关于运动过程中糖原代谢的操纵机制知之甚少。在文章2001502中，John Zhong Li，Tiemin Liu，Kingxing Kong和他的同事们发现骨骼肌中的干扰素调节因子4（IRF4）调节糖原代谢和随后的运动能力。这项工作揭示了一种调控途径，包括在控制运动能力上将IRF4 /蛋白质靶向糖原（PTG）/糖原合成。