OBJECTIVE To present the first live birth after uterine transplantation (UTx) in the People's Republic of China. DESIGN Case study. SETTING University hospital. PATIENT(S) A 22-year-old woman with Mayer-Rokitansky-Kuster-Hauser syndrome and previous surgery for vaginal reconstruction and UTx. INTERVENTION(S) Endometrial preparation, frozen embryo transfer, pregnancy follow-up, and cesarean section. MAIN OUTCOME MEASURE(S) Results of in vitro fertilization, frozen embryo transfer, ultrasound measurements during pregnancy, rejection diagnosis and treatment, delivery, live birth, and histology of uterus. RESULTS(S) Frozen embryo (cleavage stage) transfer started 1.5 years after UTx. The first embryo transfer (n = 2) resulted in a biochemical pregnancy. The second, third, and fourth embryo transfer (n = 2, 2, 3) did not result in pregnancy. The fifth embryo transfer (n = 3) resulted in pregnancy with two gestational sacs, but with spontaneous disappearance of one in early pregnancy. During early pregnancy three episodes of vaginal bleedings occurred (gestational weeks 6 + 2, 13 + 1, and 16 + 3), with a spontaneously resorbing subchorionic hematoma diagnosed at the last bleeding episode. Bleeding episodes were treated with corticosteroids and tacrolimus. During pregnancy, blood flow velocity waveforms and fetal growth parameters were normal. A subacute cesarean section was performed at gestational week 33 + 6 due to uterine contraction pattern suggesting imminent labor. A healthy boy (2,000 g) with Apgar scores of 10, 10, 10 was delivered. The uterus was kept for a possible second pregnancy. CONCLUSION(S) The first live birth after UTx in the People's Republic of China is reported and this occurred after a robotic-assisted laparoscopic uterus retrieval from the mother.

中文翻译：

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中华人民共和国子宫移植后首例活产报告

目的 介绍中华人民共和国第一例子宫移植 (UTx) 后的活产儿。设计案例研究。设置大学医院。患者 (S) 一名 22 岁女性，患有 Mayer-Rokitansky-Kuster-Hauser 综合征，之前接受过阴道重建和 UTx 手术。干预措施 子宫内膜准备、冷冻胚胎移植、妊娠随访和剖宫产。主要结局指标体外受精、冷冻胚胎移植、妊娠期超声测量、排斥诊断和治疗、分娩、活产和子宫组织学的结果。结果（S）冷冻胚胎（卵裂期）移植在 UTx 后 1.5 年开始。第一次胚胎移植（n = 2）导致生化妊娠。第二次、第三次和第四次胚胎移植（n = 2、2、3）没有导致怀孕。第 5 次胚胎移植 (n = 3) 导致妊娠有两个妊娠囊，但一个在妊娠早期自然消失。在妊娠早期，发生了 3 次阴道出血（妊娠 6 + 2、13 + 1 和 16 + 3 周），最后一次出血时诊断为自发吸收的绒毛膜下血肿。出血事件用皮质类固醇和他克莫司治疗。孕期血流速度波形和胎儿生长参数正常。由于子宫收缩模式表明即将分娩，因此在妊娠第 33 + 6 周进行了亚急性剖宫产。一名健康男孩 (2,000 g) 出生，Apgar 评分为 10、10、10。保留子宫以备第二次怀孕。结论 (S) 人类 UTx 后的第一例活产