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Mining the Antibody Repertoire for Solutions to SARS-CoV-2
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2020-10-07 , DOI: 10.1016/j.chom.2020.09.010
Wenzhao Meng 1 , Aaron M Rosenfeld 1 , Eline T Luning Prak 2
Affiliation  

In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monitor virus-specific B cells after infection or vaccination using antibody sequencing.



中文翻译:


挖掘抗体库以解决 SARS-CoV-2



在本期《Cell Host & Microbe》中,Nielsen 及其同事对重症 COVID-19 患者的抗体库进行了测序,以揭示在更大的多克隆反应背景下潜在的趋同特征。他们的研究结果表明,随着数据库的完善,有可能在感染或接种疫苗后使用抗体测序来监测病毒特异性 B 细胞。

更新日期:2020-10-07
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