EEG measures such as power and connectivity have been widely used to investigate the neuronal underpinnings of ADHD. Traditionally, the fixed band analysis, in which a single frequency band is applied to all the subjects, has been used to estimate these EEG measures. However, there are important interindividual differences in the predominant frequency of alpha-band oscillations. In this study, we present an individualized estimate of EEG in the alpha band and compared the results with traditional fixed band analysis. We also examined the EEG profile separately in lower and upper alpha bands. We further examined the association between EEG measures and ADHD symptoms. Eyes closed resting EEG was collected from 21 adolescents with clinically elevated levels of ADHD and 21 age and gender matched control subjects. Spectral power and connectivity were computed in lower and upper alpha bands. Results revealed a dissociation between upper and lower alpha band power and connectivity in ADHD. The ADHD group showed reduced power and connectivity in the lower alpha band and an elevation of upper alpha power compared to the Control group. EEG power in the lower alpha band was negatively associated with ADHD severity. Our results, however, did not provide conclusive evidence for IAF as an overall greater measure of EEG compared to the traditional fixed band method.

诸如功率和连通性之类的 EEG 测量已被广泛用于研究 ADHD 的神经元基础。传统上，固定频带分析已被用于估计这些 EEG 测量值，其中将单个频带应用于所有对象。然而，α 波段振荡的主要频率存在重要的个体差异。在这项研究中，我们提出了 alpha 波段中 EEG 的个性化估计，并将结果与​​传统的固定波段分析进行了比较。我们还分别检查了较低和较高 alpha 波段的 EEG 配置文件。我们进一步检查了 EEG 测量与 ADHD 症状之间的关联。从 21 名临床上多动症水平升高的青少年和 21 名年龄和性别匹配的对照受试者中收集闭眼静息 EEG。在较低和较高的 alpha 波段中计算了光谱功率和连接性。结果显示 ADHD 中上下 alpha 波段功率和连接性之间存在分离。与对照组相比，ADHD 组显示下阿尔法频带的功率和连通性降低，而上阿尔法功率升高。低阿尔法波段的脑电图功率与 ADHD 的严重程度呈负相关。然而，与传统的固定频带方法相比，我们的结果并没有为 IAF 作为 EEG 的整体更好的测量提供确凿的证据。低阿尔法波段的脑电图功率与 ADHD 的严重程度呈负相关。然而，与传统的固定频带方法相比，我们的结果并没有为 IAF 作为 EEG 的整体更好的测量提供确凿的证据。低阿尔法波段的脑电图功率与 ADHD 的严重程度呈负相关。然而，与传统的固定频带方法相比，我们的结果并没有为 IAF 作为 EEG 的整体更好的测量提供确凿的证据。