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Molecular Characterization of Norovirus Circulating in Northwest Mexico During 2013–2014
Food and Environmental Virology ( IF 4.1 ) Pub Date : 2020-10-07 , DOI: 10.1007/s12560-020-09446-w
Leticia Félix-Valenzuela , Alejandro Molina-Chavarria , Carmen Itzé Enríquez-Hernández , Enrique Bolado-Martínez , María de los Ángeles Durazo-Arvizu , Roberto Dórame-Castillo , Manuel Alberto Cano-Rangel , Verónica Mata-Haro

Norovirus (NoV) is an important etiological agent of diarrhea in children and adults. In Mexico, NoV screening is not routinely performed. NoV is highly infectious and is responsible for massive outbreaks due to the consumption of contaminated food. The study was a cross-sectional design. Samples of diarrheal stools were collected from (62) children and (38) adults with acute gastroenteritis during 2013–2014. The circulating genogroups of NoV were detected by amplifying the RdRp gene fragment, and for the genotyping, the capsid and polymerase fragments were sequenced. Seventy-seven percent of the analyzed samples were positive for NoV. Genotyping was possible for 51 samples; for polymerase GII.P2, GII.P31, GII.P4, GII.P7, GII.P40, and GI.P14 were identified, whereas for capsid, genotypes GI.3, GII.2, GII.4, GII.5, GII.14, and GII.17. In conclusion, there is a high prevalence of gastroenteritis due to NoV in the northwest of Mexico, including genotypes that have not been reported previously in Mexico.



中文翻译:

2013-2014年在墨西哥西北部传播的诺如病毒的分子特征

诺如病毒(NoV)是儿童和成人腹泻的重要病因。在墨西哥,不定期进行NoV筛查。NoV具有高度传染性,并由于食用受污染的食物而导致大规模爆发。该研究是横断面设计。在2013-2014年期间,从(62)儿童和(38)成人急性肠胃炎中收集了腹泻粪便样本。通过扩增RdRp基因片段来检测NoV的循环基因组,并进行衣壳和聚合酶片段的基因分型。77%的分析样品中NoV呈阳性。基因分型有可能用于51个样品。对于聚合酶GII.P2,GII.P31,GII.P4,GII.P7,GII.P40和GI.P14,已鉴定出,而对于衣壳而言,基因型为GI.3,GII.2,GII.4,GII.5, GII.14和GII.17。结论,

更新日期:2020-10-07
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