A non-enzymatic chemical sensor for lactate (LA) detection based on an extended-gate type organic field-effect transistor (OFET) is reported. The proposed device is composed of an extended-gate electrode modified by an artificial receptor phenylboronic acid derivative as the detection part and the OFET as the drive part. The mechanism of LA detection relies on the changes in transfer characteristics of the OFET upon dynamic covalent bonding with LA. After evaluating the ability of the device to detect LA, it was applied to the selectivity study. This report proved the possibility of using the OFET-based sensor device for non-enzymatic LA detection.

中文翻译：

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扩展门型有机场效应晶体管的非酶乳酸检测

报告了一种基于扩展栅型有机场效应晶体管（OFET）的用于乳酸（LA）检测的非酶化学传感器。所提出的装置包括由人工受体苯基硼酸衍生物修饰的延伸栅电极作为检测部分，并由OFET作为驱动部分。LA检测的机制依赖于与LA动态共价键合时OFET传递特性的变化。在评估设备检测LA的能力之后，将其应用于选择性研究。该报告证明了使用基于OFET的传感器设备进行非酶促LA检测的可能性。