Abstract For the first time, the technological aspects of the highly productive and selective synthesis of UV-reactive poly(ethylene glycol) mono-1-propenyl ether monomers was developed. The solvent-free isomerization of model commercial available 2-allyloxyethanol and allyloxypoly(ethylene glycol) derivatives, type Allyl–[OCH2CH2]n–OH, n = 1–5, into a 1-propenyl derivative under the homogeneous catalysis conditions using the ruthenium complexes were evaluated. The effect of a various reaction conditions (i.e. the concentration of [Ru] complex, the reaction temperature, reaction gas atmosphere) together with trace amounts of allyl hydroperoxides formed via autoxidation reaction of allyl substrates on the productivity of catalyst was examined in detail. Moreover, the significant role of the allyl substrate structures on the catalytic activity of ruthenium catalysts were also recognized. The optimal parameters of the scaled-up synthesis together with productivity of catalyst were first established.

中文翻译：

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合成聚（乙二醇）单-1-丙烯基醚单体的技术方面

摘要 首次开发了高产和选择性合成紫外线反应性聚（乙二醇）单-1-丙烯基醚单体的技术方面。使用钌在均相催化条件下将模型商业上可用的 2-烯丙氧基乙醇和烯丙氧基聚（乙二醇）衍生物（烯丙基-[OCH2CH2]n-OH，n = 1-5）无溶剂异构化为 1-丙烯基衍生物复合物进行了评估。详细研究了各种反应条件(即[Ru]配合物的浓度、反应温度、反应气体气氛)以及通过烯丙基底物的自氧化反应形成的痕量烯丙基氢过氧化物对催化剂生产率的影响。而且，还认识到烯丙基底物结构对钌催化剂的催化活性的重要作用。首先确定了放大合成的最佳参数以及催化剂的生产率。