Abstract

Present study investigated the interactive effect of swimming training and fenugreek on glycemic index and lipid profile of diabetic rats. Forty-eight diabetic rats were randomly assigned to (1) control(C), (2) training(T), (3) fenugreek(F), and (4) training + fenugreek(T + F) groups and 12 healthy rats were placed in healthy control (HC) group. During 4 weeks, groups 2 and 4 performed swimming training for 5 sessions per week and groups 3 and 4 received 100 mg/kg fenugreek. training, fenugreek and training + fenugreek significantly decreased glucose, insulin, insulin resistance, LDL, VLDL, TG and TC as well as increased HDL (p ≤ .05) also training + fenugreek had more favourable effects on improving glycemic indices and lipid profile compared to training and fenugreek alone (p ≤ .05). It seems that training and fenugreek alone or synergistically improve the glycemic indices and lipid profile in diabetic rats, nevertheless the synergistic effects of training and fenugreek can be more desirable than the effect of each alone.

摘要

本研究调查了游泳训练和胡芦巴对糖尿病大鼠血糖指数和血脂谱的相互作用。48 只糖尿病大鼠被随机分配到 (1) 对照组 (C)、(2) 训练组 (T)、(3) 胡芦巴 (F) 和 (4) 训练 + 胡芦巴 (T + F) 组和 12 只健康大鼠置于健康对照组（HC）组。在 4 周内，第 2 组和第 4 组每周进行 5 次游泳训练，第 3 组和第 4 组接受 100 mg/kg 胡芦巴。训练、胡芦巴和训练+胡芦巴显着降低葡萄糖、胰岛素、胰岛素抵抗、LDL、VLDL、TG 和 TC 以及增加 HDL ( p  ≤ .05) 与相比，训练+胡芦巴对改善血糖指数和血脂状况有更有利的影响单独训练和葫芦巴（p ≤ .05)。似乎训练和葫芦巴单独或协同改善糖尿病大鼠的血糖指数和血脂水平，但训练和胡芦巴的协同作用可能比单独使用的效果更令人满意。