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Green biosynthesis of silver nanoparticle using Commiphora myrrh extract and evaluation of their antimicrobial activity and colon cancer cells viability
Journal of King Saud University-Science ( IF 3.8 ) Pub Date : 2020-10-06 , DOI: 10.1016/j.jksus.2020.09.024
Mona S. Alwhibi , Dina A. Soliman , Hala al khaldy , Aljohara Alonaizan , Najat Abdulhaq Marraiki , Mohamed El-Zaidy , Moodi S. AlSubeie

There is increasing attention directed to mineral nanoparticle for intensive applications in various fields of science, such as medicine, chemistry, agriculture, and biotechnology. There is also a growing attentiveness to the use of eco-friendly methods to synthesize nanoparticle without making or using environmentally dangerous substances to human health. This article describes the biological methods for green synthesis using Commiphora myrrha silver nanoparticle (AgNP) extract. C. myrrha-synthesized AgNPs, which were completed by exposing myrrh aqueous extract to silver nitrate, were characterized by transmission electron microscopy, Fourier transform infrared spectroscopy, Zetasizer, and ultraviolet–visible spectral analyses. AgNPs were characterized by varying the color of the solution from light yellow to brown and then depicting the surface plasmon-resonance peaks at 445 nm. This study has promising results in the treatment of colon cancer, as it has impressive outcomes using different concentrations of AgNPs in 100 μl medium (30%) compared to control (100%). The results also showed increasing inhibition zones of antibacterial activity with AgNPs in Enterococcus faecalis (59 mm) and Bacillus cereus (51 mm) compared to myrrh aqueous extract. Fungi that were screened for growth inhibition zones were Fusarium oxysporum (20 mm), Alternaria alternata (14 mm), and Trichoderma (10 mm).



中文翻译:

香附没药提取物绿色生物合成银纳米颗粒及其抗菌活性和结肠癌细胞活力评估

对于在各种科学领域,例如医学,化学,农业和生物技术中广泛应用的矿物纳米颗粒,越来越引起关注。人们越来越关注使用生态友好的方法来合成纳米粒子,而不制造或使用对人体健康有害的环境物质。本文介绍了使用没药没药进行绿色合成的生物学方法银纳米颗粒(AgNP)提取物。C.没药合成的AgNPs,通过将没药的水提取物暴露于硝酸银中而完成,通过透射电子显微镜,傅立叶变换红外光谱,Zetasizer和紫外可见光谱分析进行表征。通过将溶液的颜色从浅黄色变为棕色,然后描绘在445 nm处的表面等离振子共振峰来表征AgNP。这项研究在结肠癌的治疗中具有令人鼓舞的结果,因为与对照(100%)相比,在100μl培养基(30%)中使用不同浓度的AgNPs具有令人印象深刻的结果。结果还显示,粪肠球菌(59毫米)和蜡状芽孢杆菌中AgNPs的抗菌活性抑制区增加。(51 mm)与没药水提取物相比。筛选出生长抑制区的真菌是尖孢镰刀菌(20毫米),链格孢菌(14毫米)和木霉菌(10毫米)。

更新日期:2020-11-12
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