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Can Microbes Boost Tregs to Suppress Food Sensitivities?
Trends in Immunology ( IF 13.1 ) Pub Date : 2020-10-06 , DOI: 10.1016/j.it.2020.09.005
Magdalena Siller , Yanlin Zeng , Reinhard Hinterleitner

Food sensitivities are on the rise worldwide. Peripheral induced regulatory T cells (pTreg cells) play a central role in oral tolerance to dietary antigens and can contribute to preventing the onset of immune-mediated food sensitivities. Here, we discuss the potential of microbial-derived products in promoting pTreg cell proliferation for re-establishing oral tolerance in immune-mediated food sensitivities.



中文翻译:

微生物可以增加Treg抑制食物敏感性吗?

在世界范围内,食品敏感性正在上升。外周诱导的调节性T细胞(pTreg细胞)在口服对饮食抗原的耐受性中起着核心作用,并有助于防止免疫介导的食物敏感性的发作。在这里,我们讨论了微生物来源的产品在促进pTreg细胞增殖以重新建立免疫介导的食物敏感性的口服耐受性方面的潜力。

更新日期:2020-10-30
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