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Structures from the Mesophase: MicroED Targets Crystals Extracted from LCP
Structure ( IF 4.4 ) Pub Date : 2020-10-06 , DOI: 10.1016/j.str.2020.09.005
Marcus Gallagher-Jones , Jose A. Rodriguez

The determination of protein structures from nanocrystals grown in lipidic cubic phase (LCP) is a promising crystallographic approach. In this issue of Structure, Zhu et al. (2020) extract crystals from the dense matrix of monoolein LCP for interrogation by micro electron diffraction (MicroED) and yield a 2 Å structure of Proteinase K.



中文翻译:

中间相的结构:MicroED靶向从LCP提取的晶体

从脂质立方相(LCP)中生长的纳米晶体确定蛋白质结构是一种很有前途的晶体学方法。在本期《结构》中,Zhu等人。(2020)从单油精LCP的致密基质中提取晶体,以便通过微电子衍射(MicroED)进行询问,并产生2 K的蛋白酶K结构。

更新日期:2020-10-06
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