Abstract The morphology of nanomaterials combines the characteristics of their size, shape and spatial structure. Owing to the improved spatiotemporal control of the nanocarriers for anti-cancer drug delivery, the morphology adaptive nanomaterials have received tremendous attention in the field of nanomedicine, while they are able to respond through chemical or physical change. In this review, we summarize the recent advancements of morphology adaptive nanomaterials and their application in anti-cancer drug delivery system, wherein the size, shape and spatial structure of nanocarriers can be changed to adapt the complex living system, thus overcoming the pathological barriers in drug delivery. The overview of the recent examples shows that each step of delivery process can be improved by the morphology adaption, which represents the great potential for clinic translation of morphology adaptive nanomaterials.

中文翻译：

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形态自适应纳米材料用于抗癌药物递送的新进展

摘要 纳米材料的形貌综合了其尺寸、形状和空间结构的特点。由于用于抗癌药物递送的纳米载体的时空控制得到改善，形态适应性纳米材料在纳米医学领域受到了极大的关注，同时它们能够通过化学或物理变化做出反应。在这篇综述中，我们总结了形态适应性纳米材料的最新进展及其在抗癌药物递送系统中的应用，其中纳米载体的大小、形状和空间结构可以改变以适应复杂的生命系统，从而克服病理障碍。药物输送。最近例子的概述表明，交付过程的每一步都可以通过形态适应来改进，