An environmental friendly synthetic route for potassium alum catalyzed one-pot multi-component synthesis of biologically active 2-oxo(thio)-1,2,3,4-tetrahydropyrimidines and N--aryl-3-aminodihydropyrrol-2-one-4-carboxylates has developed. The present synthetic route has the notable advantages of natural, mineral, inexpensive and non-toxic catalyst, mild reaction conditions, eco-friendly, one-pot and good to high yield of biological active products. This method is simple for work up and the compound formed filtered and purified just by simple crystallization.

中文翻译：

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铝矾土可自然，经济地催化一锅，多组分和清洁合成2-氧代（硫代）-1,2,3,4-四氢嘧啶和N-芳基-3-氨基二氢吡咯-2-酮-4-羧酸盐

钾明矾催化生物活性2-氧代（硫代）-1,2,3,4-四氢嘧啶和N-芳基-3-氨基二氢吡咯-2-酮-4的一锅多组分合成的环保合成路线-羧酸盐已发展。本发明的合成路线具有天然，矿物，廉价且无毒的催化剂，反应条件温和，生态友好，一锅法和良好至高产率的生物活性产物的显着优点。该方法易于后处理，仅通过简单的结晶就可以过滤和纯化形成的化合物。