Introduction. This study investigated the influence of lockdown during the 2019 coronavirus disease (COVID-19) pandemic on the quality of life of patients with Parkinson’s disease (PD). Methods. We conducted a questionnaire survey involving 113 patients with PD from Xihu District, Hangzhou, Zhejiang. During the epidemic prevention and control period (February 1 to March 31, 2020), patients enrolled were asked to fill out questionnaires, including the “COVID-19 Questionnaire for PD Patients during the Period of Epidemic Prevention and Control” and “39-item Parkinson’s Disease Questionnaire (PDQ-39).” During the phase of gradual release of epidemic prevention and control (April 1 to April 30, 2020), all patients were followed up again, and PDQ-39 questionnaires were completed. Results. The quality of life for patients during the period of epidemic prevention and control was worse than that after epidemic prevention and control ( < 0.001). The biggest problem that they faced was that they could not receive their doctor’s advice or guidance regularly. The quality of life of patients who had difficulty getting doctors’ guidance or those who changed their routine medication due to lockdown was even worse. Telemedicine was quite effective and efficient for patients to get doctors’ guidance during lockdown. Conclusions. The inconvenient treatment during the pandemic directly caused the aggravation of patients’ symptoms and the decline in their quality of life. It is suggested that social media (such as WeChat or Tencent QQ) are used for regular interactions and follow-up appointments for patients with inconvenient medical treatment.

中文翻译：

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COVID-19 大流行对帕金森病患者生活质量的影响

简介。本研究调查了 2019 年冠状病毒病 (COVID-19) 大流行期间封锁对帕金森病 (PD) 患者生活质量的影响。方法。我们对来自浙江省杭州市西湖区的 113 名 PD 患者进行了问卷调查。疫情防控期间（2020年2月1日至3月31日），要求入组患者填写《疫情防控期间PD患者COVID-19问卷》和《39项问卷》。帕金森病问卷 (PDQ-39)。” 在疫情防控逐步放开阶段（2020年4月1日至4月30日）对所有患者进行再次随访，完成PDQ-39问卷调查。结果. 疫情防控期间患者生活质量较疫情防控后差（ <0.001）。他们面临的最大问题是他们无法定期接受医生的建议或指导。难以获得医生指导的患者或因封锁而改变常规药物的患者的生活质量更差。远程医疗对于患者在锁定期间获得医生的指导非常有效和高效。结论. 疫情期间治疗不便，直接导致患者症状加重，生活质量下降。对于不便就医的患者，建议通过社交媒体（如微信或腾讯QQ）进行定期互动和随访预约。