Abstract

One new piperazinedione derivative, nigerpiperazine A (1), along with six known compounds (2–7) were isolated from the fungus Aspergillus niger JX-5 from mangrove Ceriops tagal. Nigerpiperazine A (1) was elucidated by spectroscopic analyses and ¹³C NMR chemical shift calculations, compounds 4 and 5 were determined by X-ray and the CD spectra. The absolute configuration of 4 was identified by X-ray for the first time. Compounds 1 and 4 showed inhibitory activities against Helicoverpa armigera Hubner with the IC₅₀ values of 200 and 100 µg/mL, respectively.

中文翻译：

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从红树林衍生的真菌黑曲霉JX-5中分离出一种新的哌嗪二酮

摘要

从红树林Ceriops tagal的真菌Aspergillus niger JX-5中分离出一种新的哌嗪二酮衍生物，nigerpiperazine A ( 1 ) 以及六种已知化合物 ( 2-7 ) 。Nigerpiperazine A ( 1 ) 通过光谱分析和¹³ C NMR化学位移计算得到阐明，化合物4和5通过X射线和CD光谱确定。4的绝对构型首次通过X射线识别。化合物1和4对棉铃虫具有抑制活性，IC_{为 50}值分别为 200 和 100 µg/mL。