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Long‐term exposure to indoor air pollution and risk of tuberculosis
Indoor Air ( IF 5.8 ) Pub Date : 2020-10-05 , DOI: 10.1111/ina.12756
Vidhiben Patel 1 , Andrew Foster 2 , Alison Salem 1 , Amit Kumar 3 , Vineet Kumar 3 , Biplab Biswas 4 , Mehdi Mirsaeidi 1, 5 , Naresh Kumar 1
Affiliation  

Indoor air pollution (IAP) is a recognized risk factor for various diseases. This paper examines the role of indoor solid fuel exposure in the risk of mycobacterium tuberculosis (TB) in Delhi Metropolitan, India. Using a cross‐sectional design, subjects were screened for a history of active TB and lifelong exposure to IAP sources, such as solid fuel burning and kerosene. The TB prevalence rate in the study area was 1117 per 100 000 population. Every year, increase in solid fuel exposure was associated with a three percent higher likelihood of a history of active TB. Subjects exposed to solid fuel and kerosene use for both heating home and cooking showed significant associations with TB. Age, household expenditure (a proxy of income), lung function, and smoking also showed significant associations with TB. Smokers and solid fuel–exposed subjects were four times more likely to have a history of active TB than non‐smoker and unexposed subjects. These finding calls strategies to mitigate solid fuel exposure, such as use of clean cookstove and ventilation, to mitigate the risk of TB which aligns with the United Nations’ goal of “End TB by 2030.”

中文翻译:

长期暴露于室内空气污染和患肺结核的风险

室内空气污染 (IAP) 是公认的各种疾病的危险因素。本文研究了印度德里大都会室内固体燃料暴露在结核分枝杆菌 (TB) 风险中的作用。使用横断面设计,对受试者进行活动性结核病史和终生接触 IAP 源(如固体燃料燃烧和煤油)的筛查。研究区的结核病患病率为每 10 万人中有 1117 人。每年,固体燃料暴露的增加与活动性结核病史的可能性增加 3% 相关。暴露于固体燃料和煤油用于家庭取暖和烹饪的受试者显示出与结核病的显着关联。年龄、家庭支出(收入的代表)、肺功能和吸烟也与结核病显着相关。吸烟者和接触固体燃料的受试者患活动性结核病的可能性是不吸烟者和未接触固体燃料的受试者的四倍。这些发现呼吁采取减少固体燃料暴露的策略,例如使用清洁炉灶和通风,以降低结核病的风险,这符合联合国“到 2030 年终结结核病”的目标。
更新日期:2020-10-05
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