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Screening method to prioritize relevant bio‐based acids and their biochemical processes using recent patent information
Biofuels, Bioproducts and Biorefining ( IF 3.2 ) Pub Date : 2020-10-05 , DOI: 10.1002/bbb.2156
Melissa Braga 1, 2 , Priscila M. Ferreira 3 , João Ricardo M. Almeida 1, 2, 4
Affiliation  

There are increasing environmental and economic demands for the production of chemicals of industrial interest from renewable resources. Among the renewable products, short‐chain carboxylic acids (C1‐C6) stand out due to their importance in many sectors of the economy. Within this class, a wide variety of acids are industrially valuable as the precursors of many other chemicals for different applications, technological solutions, and markets. This makes it difficult to identify the most promising from a technical and economic standpoint. In this work, data on scientific papers and patents published between 2008 to 2017, related to the main bio‐based carboxylic acids, are used to identify the acids that are generating growing scientific and industrial interest. The biochemical processes in patents associated with the production of such acids are evaluated using a multicriteria approach that integrates valuation patent criteria. The results of this study show that acids that are of substantial commercial interest, such as acetic, citric, lactic, acrylic, and methacrylic acids, have the highest growth rate both in scientific papers and patents. In terms of biochemical processes, the multicriteria decision analysis showed that the most relevant processes described in patents were associated with ‘drop‐in’ acids such as methacrylic, adipic, maleic, acrylic, and glutaric acids. There is also a clear indication of the emergence of studies on low volume acids such as acetoacetic, acetolactic, muconic, and levulinic acids. In conclusion, the analysis shows that emerging scientific and technological production is conservative, focusing on acids with established markets, especially for the substitution of petrochemicals for immediate demand. © 2020 Society of Industrial Chemistry and John Wiley & Sons Ltd

中文翻译:

使用最新专利信息筛选相关生物基酸及其生化过程的优先顺序的方法

从可再生资源生产具有工业价值的化学品的环境和经济需求不断增长。在可再生产品中,短链羧酸(C1-C6)因其在经济的许多领域中的重要性而脱颖而出。在这一类别中,各种各样的酸作为许多其他化学品的前体在工业上具有价值,可用于不同的应用,技术解决方案和市场。从技术和经济角度看,这很难确定最有前途的东西。在这项工作中,使用2008年至2017年之间发表的与主要生物基羧酸有关的科学论文和专利数据,来识别引起科学和工业兴趣增长的酸。使用整合评估专利标准的多标准方法评估与此类酸生产相关的专利中的生化过程。这项研究的结果表明,在科学论文和专利中,具有重大商业价值的酸(例如乙酸,柠檬酸,乳酸,丙烯酸和甲基丙烯酸)具有最高的增长率。在生化过程方面,多标准决策分析表明,专利中描述的最相关的过程与“直接”酸有关,例如甲基丙烯酸,己二酸,马来酸,丙烯酸和戊二酸。也清楚地表明了对低体积酸如乙酰乙酸,乙酰乳酸,粘康酸和乙酰丙酸的研究的出现。结论,分析表明,新兴的科学技术生产是保守的,重点放在具有成熟市场的酸上,尤其是用石化产品代替即时需求。©2020工业化学学会和John Wiley&Sons Ltd
更新日期:2020-10-05
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