A porous water-compatible molecularly imprinted polymer (MIP) coating using catechol as a pseudo-template and a water-soluble functional monomer (4-vinyl benzoic acid) with ethylene glycol dimethacrylate as the crosslinker was developed for extraction of phenols from environmental water samples. The MIP devices were combined with ultra high performance liquid chromatography with a photodiode array detector (UHPLC-PDA) suitable for the simultaneous determination of trace levels of phenolic compounds with a wide range of polarities —phenol, alkylphenols and chlorophenols— in seawater and produced water. Parameters that influence extraction efficiency (salinity, pH, polymer mass, desorption solvent, and desorption time) were optimized to give method detection limits (LOD) ranging from 0.1 to 2 μg L⁻¹ and linearity (R²>0.99) over at least three orders of magnitude for the hydrophobic phenols (e.g., 0.5–1000 μg L⁻¹ for 2,4,6-trichlorophenol) and ~2 orders of magnitude for the light phenols (e.g., 10–120 μg L⁻¹ for phenol, 5–120 μg L⁻¹ for methylphenols and 2-chlorophenol, 0.5–120 μg L⁻¹ 3-methyl-4-chlorophenol and 2,4-dichlorophenol). The recoveries from authentic spiked samples ranged from 85 to 100% with %RSDs of 0.2–14% for seawater and 81–107% with %RSD of 0.1–11% for produced water. The resulting MIP-based extraction requires no pre-conditioning of the sorbent, and because the required sample size is small and sample manipulation is limited, the method is easy to multiplex for high throughput sample processing.

开发了一种以邻苯二酚为伪模板，水溶性功能单体（4-乙烯基苯甲酸）和乙二醇二甲基丙烯酸酯为交联剂的多孔水相容性分子印迹聚合物（MIP）涂层，用于从环境水样品中提取酚。MIP设备与超高效液相色谱仪和光电二极管阵列检测器（UHPLC-PDA）相结合，适用于同时测定海水和采出水中痕量水平的多种极性酚类化合物（苯酚，烷基酚和氯酚） 。优化了影响萃取效率的参数（盐度，pH，聚合物质量，解吸溶剂和解吸时间），以提供方法检测限（LOD），范围为0.1至2μgL ^-1对于疏水性酚（例如，对于2,4,6-三氯酚为0.5–1000μgL ^-1），线性度（R ² > 0.99）至少在三个数量级以上；对于轻质酚（例如，酚醛化合物）为〜2个数量级，10-120微克大号^-1苯酚，5-120微克大号^-1为甲基酚类和2-氯苯酚，0.5-120微克大号^-13-甲基-4-氯苯酚和2,4-二氯苯酚）。真实加标样品的回收率范围为85％至100％，海水的RSSD百分比为0.2％至14％，采出水的RSSD的百分比为81％至107％的0.1％至11％。所得的基于MIP的萃取无需对吸附剂进行预处理，并且由于所需的样品量小且样品处理受到限制，因此该方法易于多路复用以进行高通量样品处理。