The Afirma test has been used in the diagnosis of cytologically indeterminate thyroid nodules to reduce diagnostic uncertainty and unnecessary surgeries. Gene Sequencing Classifier (GSC) was developed to improve the positive predictive value and overall test performance of Gene Expression Classifier (GEC). Here we present our experience comparing the performance of first‐generation assay of Afirma (GEC) with the new assay (GSC).

中文翻译：

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Afirma 基因表达分类器与基因测序分类器在不确定甲状腺结节中的比较：单一机构的经验

Afirma 测试已用于诊断细胞学不确定的甲状腺结节，以减少诊断的不确定性和不必要的手术。开发基因测序分类器 (GSC) 以提高基因表达分类器 (GEC) 的阳性预测值和整体测试性能。在这里，我们展示了我们比较 Afirma 第一代检测 (GEC) 与新检测 (GSC) 性能的经验。