In this study, various calorimetric and analytical techniques were used to evaluate the thermodynamics of the preparation of adipic acid through the oxidation with hydrogen peroxide. The reaction exotherm was combined with the reaction mechanism. Differential scanning calorimetry revealed that the hydrogen peroxide was relatively stable when Na₂WO₄.2H₂O and H₂SO₄ were used as cocatalysts. Reaction calorimetry, in situ Fourier transform infrared spectroscopy and gas chromatography/mass spectrometry (GC/MS) results indicated a possible macroscopic reaction pathway at 73 and 90°C stage. Furthermore, the results obtained through adiabatic calorimeter (Phi‐TEC II) and GC/MS indicated the possibility of catastrophic accidents if control of the target reaction was lost. The criticality classes of this reaction were of Grade 5. The results of this study can be further used to improve the inherent safety of its operating measures, as a result, this reaction process can be scaled up.

中文翻译：

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过氧化氢氧化制备己二酸的热危害及反应机理

在这项研究中，各种量热和分析技术被用来评估通过过氧化氢氧化制备己二酸的热力学。反应放热与反应机理结合在一起。差示扫描量热法显示，当Na ₂ WO ₄ .2H ₂ O和H ₂ SO ₄时，过氧化氢相对稳定。被用作助催化剂。反应量热法，原位傅里叶变换红外光谱和气相色谱/质谱（GC / MS）结果表明，在73和90°C阶段可能存在宏观反应途径。此外，通过绝热热量计（Phi-TEC II）和GC / MS获得的结果表明，如果失去对目标反应的控制，则可能发生灾难性事故。该反应的临界等级为5级。该研究结果可以进一步用于改善其操作措施的固有安全性，因此，该反应过程可以扩大规模。