Mycotoxins are a great potential threat to human health, and the progress in the development of mycotoxin detection methods is of an escalating importance with the increasing emphasis on food safety. Aptamer, performing the same function as antibody in specific binding with targets, exhibits profound potential in biosensing since its debut in 1990. Recent years have witnessed the rapid development of aptasensors for mycotoxin detection with the achievement of ultralow limit of detection and high sensitivity in the lab. However, there is still no officially approved aptasensing methods in mycotoxin detection application. In order to provide researchers with inspirations in the design and development of aptasensors for mycotoxin detection, we divide these aptasensors into two types, namely “on the surface” and “in the colloid”, according to the location where the key sensing reaction occurs. We also systematically review aptasensors reported in the past 5 years under the abovementioned criterion of classification, and compare the advantages and disadvantages of each kind of aptasensors. Finally, we discuss prospective directions in the development of aptasensors for mycotoxin detection. This paper will offer insight and motivation to practitioners working on the research and practical application of aptasensors in the detection of mycotoxins and other substances.

霉菌毒素是对人类健康的巨大潜在威胁，随着对食品安全的日益重视，霉菌毒素检测方法的发展日益重要。自1990年首次亮相以来，Aapter在与靶标的特异性结合中具有与抗体相同的功能，在生物传感方面具有深远的潜力。近年来，目睹了适用于霉菌毒素检测的适体传感器的快速发展，实现了超低检测限和高灵敏度。实验室。但是，在真菌毒素检测应用中仍然没有官方认可的适体方法。为了给研究人员启发设计和开发用于检测真菌毒素的适配子，我们将这些适配子分为“表面”和“胶体”两类，根据按键感应反应发生的位置。我们还根据上述分类标准，系统地回顾了过去5年中报告的适体传感器，并比较了每种适体传感器的优缺点。最后，我们讨论了用于真菌毒素检测的适体传感器的发展方向。本文将为从事aptasensors在真菌毒素和其他物质检测方面的研究和实际应用的从业人员提供见识和动力。我们讨论了用于霉菌毒素检测的适体传感器的发展方向。本文将为从事aptasensors在真菌毒素和其他物质检测方面的研究和实际应用的从业人员提供见识和动力。我们讨论了用于霉菌毒素检测的适体传感器的发展方向。本文将为从事aptasensors在真菌毒素和其他物质检测方面的研究和实际应用的从业人员提供见识和动力。