Kashin-Beck disease (KBD) is a kind of chronic osteochondropathy, thought to be caused by environmental risk factors such as T-2 toxin. However, the exact aetiology of KBD remains unclear. In this study, we explored the functional relevance and biological mechanism of cartilage oligosaccharide matrix protein (COMP) in the articular cartilage damage of KBD.

中文翻译：

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COMP参与大骨节病关节软骨损伤的分子机制研究

大骨节病 (KBD) 是一种慢性骨软骨病，被认为是由 T-2 毒素等环境危险因素引起的。然而，KBD的确切病因仍不清楚。在这项研究中，我们探讨了软骨寡糖基质蛋白（COMP）在 KBD 关节软骨损伤中的功能相关性和生物学机制。