The primordial eye field of the vertebrate embryo is a single entity of retinal progenitor cells spanning the anterior neural plate before bifurcating to form bilateral optic vesicles. Here we review fate mapping data from zebrafish suggesting that prior to evagination of the optic vesicles the eye field may undergo a Maypole-plait migration of progenitor cells through the midline influenced by the anteriorly subducting diencephalon. Such an enigmatic translocation of scaffolding progenitors could have evolutionary significance if pointing, by way of homology, to an ancient mechanism for transition of the single eye field in chordates to contralateral eye fields in vertebrates.

中文翻译：

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脊椎动物原始眼场的神秘易位

脊椎动物胚胎的原始眼场是视网膜祖细胞的单个实体，其在分叉形成双侧视神经小泡之前跨越前神经板。在这里，我们回顾了来自斑马鱼的命运图谱数据，这表明在视泡撤离之前，眼场可能会受到前减影二脑的影响而通过中线发生祖细胞的迈普尔褶状迁移。如果通过同源性指出脊椎动物脊索中单眼视野向对侧眼视野过渡的古老机制，那么这种脚手架祖细胞的神秘易位可能具有进化意义。