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Molecularly imprinted polymers in biological applications.
Biotechniques ( IF 2.2 ) Pub Date : 2020-10-01 , DOI: 10.2144/btn-2020-0091
Zahra El-Schich 1 , Yuecheng Zhang 1, 2 , Marek Feith 1, 3 , Sarah Beyer 1, 2 , Louise Sternbæk 1, 2, 4 , Lars Ohlsson 1, 2 , Maria Stollenwerk 1, 2 , Anette Gjörloff Wingren 1, 2
Affiliation  

Molecularly imprinted polymers (MIPs) are currently widely used and further developed for biological applications. The MIP synthesis procedure is a key process, and a wide variety of protocols exist. The templates that are used for imprinting vary from the smallest glycosylated glycan structures or even amino acids to whole proteins or bacteria. The low cost, quick preparation, stability and reproducibility have been highlighted as advantages of MIPs. The biological applications utilizing MIPs discussed here include enzyme-linked assays, sensors, in vivo applications, drug delivery, cancer diagnostics and more. Indeed, there are numerous examples of how MIPs can be used as recognition elements similar to natural antibodies.

中文翻译:

生物应用中的分子印迹聚合物。

分子印迹聚合物(MIP)目前被广泛使用并进一步开发用于生物应用。MIP 合成过程是一个关键过程,并且存在多种协议。用于印记的模板从最小的糖基化聚糖结构甚至氨基酸到完整的蛋白质或细菌不等。低成本、快速制备、稳定性和可重复性已成为 MIPs 的优势。此处讨论的利用 MIP 的生物学应用包括酶联分析、传感器、体内应用、药物输送、癌症诊断等。事实上,有许多关于 MIP 如何用作类似于天然抗体的识别元件的例子。
更新日期:2020-10-03
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