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Factors affecting the severity of the apnea hypoapnea index: a retrospective study on 838 Egyptian patients diagnosed with obstructive sleep apnea
The Egyptian Journal of Bronchology Pub Date : 2020-10-01 , DOI: 10.1186/s43168-020-00034-x
Ahmed Gharib , Shahira Loza

Obstructive sleep apnea (OSA) is a common condition in the general population that is highly correlated to obesity, and it is associated with major cardiovascular morbidity and mortality. In Egypt, obesity rates are known to be high; however, OSA remains largely under-diagnosed, and data on its current magnitude is very scarce. Thus, the aims of the study were to identify the percentage of OSA in a large sample of patients referred for polysomnography and to determine the effect of different demographic data on the severity of the disease. This retrospective study included 1012 patients. Medical data were reviewed by sleep specialists. The correlation between age, body mass index (BMI), and neck circumference (NC) with apnea hypoapnea index (AHI) was explored. Also, gender differences were analyzed. A total of 838 patients (81% males, 19% females) were diagnosed with OSA. Patients with mild, moderate, and severe OSA were 204 (24%), 146 (17%), and 488 (58%), respectively. Females were older than males (58.87 ± 10.25 versus 54.39 ± 22.96, p = 0.001) and BMI was not significantly different between both sexes (34.18 ± 13.53 versus 36.73 ± 23.25, p = 0.07), but NC was higher in men (43.56 ± 5.3 versus 39.34 ± 4.41, p = 0.001). AHI was significantly increased in men compared to women (47.97 ± 31.22 versus 37.95 ± 31.72, p = 0.001) and severe OSA was commonly diagnosed in men than women (p = 0.001). A positive significant correlation was found between BMI, NC with AHI, arousal index, average SpO2, and desaturation index. OSA is highly prevalent among our patients. Additionally, BMI and NC independently affected the severity of their disease.

中文翻译:

影响呼吸暂停低通气指数严重程度的因素:838例诊断为阻塞性睡眠呼吸暂停的埃及患者的回顾性研究

阻塞性睡眠呼吸暂停(OSA)是普通人群中的常见疾病,与肥胖高度相关,并且与主要的心血管疾病和死亡率相关。在埃及,肥胖率很高。但是,OSA在很大程度上仍未得到充分诊断,并且有关其当前数量的数据非常匮乏。因此,该研究的目的是确定接受多导睡眠图检查的大量患者中OSA的百分比,并确定不同人口统计学数据对疾病严重程度的影响。这项回顾性研究包括1012例患者。睡眠专家对医疗数据进行了审查。探索了年龄,体重指数(BMI)和颈围(NC)与呼吸暂停低通气指数(AHI)之间的相关性。此外,分析了性别差异。共有838位患者(男性占81%,19%的女性被诊断出患有OSA。患有轻度,中度和重度OSA的患者分别为204(24%),146(17%)和488(58%)。女性比男性大(58.87±10.25 vs 54.39±22.96,p = 0.001),男女的BMI没有显着差异(34.18±13.53 vs 36.73±23.25,p = 0.07),但男性的NC较高(43.56± 5.3对39.34±4.41,p = 0.001)。与女性相比,男性的AHI显着增加(47.97±31.22对37.95±31.72,p = 0.001),男性通常比女性诊断为严重OSA(p = 0.001)。在BMI,NC与AHI,唤醒指数,平均SpO2和去饱和指数之间发现正相关。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。中度和重度OSA分别为204(24%),146(17%)和488(58%)。女性比男性大(58.87±10.25 vs 54.39±22.96,p = 0.001),男女的BMI没有显着差异(34.18±13.53 vs 36.73±23.25,p = 0.07),但男性的NC较高(43.56± 5.3对39.34±4.41,p = 0.001)。与女性相比,男性的AHI显着增加(47.97±31.22对37.95±31.72,p = 0.001),男性通常比女性诊断为严重OSA(p = 0.001)。在BMI,NC与AHI,唤醒指数,平均SpO2和去饱和指数之间发现正相关。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。中度和重度OSA分别为204(24%),146(17%)和488(58%)。女性比男性大(58.87±10.25 vs 54.39±22.96,p = 0.001),男女的BMI没有显着差异(34.18±13.53 vs 36.73±23.25,p = 0.07),但男性NC较高(43.56± 5.3对39.34±4.41,p = 0.001)。与女性相比,男性的AHI显着增加(47.97±31.22对37.95±31.72,p = 0.001),男性通常比女性诊断为严重OSA(p = 0.001)。BMI,NC与AHI,唤醒指数,平均SpO2和去饱和指数之间存在显着正相关。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。女性比男性大(58.87±10.25 vs 54.39±22.96,p = 0.001),男女的BMI没有显着差异(34.18±13.53 vs 36.73±23.25,p = 0.07),但男性的NC较高(43.56± 5.3对39.34±4.41,p = 0.001)。与女性相比,男性的AHI显着增加(47.97±31.22对37.95±31.72,p = 0.001),男性通常比女性诊断为严重OSA(p = 0.001)。在BMI,NC与AHI,唤醒指数,平均SpO2和去饱和指数之间发现正相关。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。女性比男性大(58.87±10.25 vs 54.39±22.96,p = 0.001),男女的BMI没有显着差异(34.18±13.53 vs 36.73±23.25,p = 0.07),但男性NC较高(43.56± 5.3对39.34±4.41,p = 0.001)。与女性相比,男性的AHI显着增加(47.97±31.22对37.95±31.72,p = 0.001),男性通常比女性诊断为严重OSA(p = 0.001)。BMI,NC与AHI,唤醒指数,平均SpO2和去饱和指数之间存在显着正相关。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。但男性的NC较高(43.56±5.3对39.34±4.41,p = 0.001)。与女性相比,男性的AHI显着增加(47.97±31.22对37.95±31.72,p = 0.001),男性通常比女性诊断为严重OSA(p = 0.001)。在BMI,NC与AHI,唤醒指数,平均SpO2和去饱和指数之间发现正相关。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。但男性的NC较高(43.56±5.3对39.34±4.41,p = 0.001)。与女性相比,男性的AHI显着增加(47.97±31.22对37.95±31.72,p = 0.001),男性通常比女性诊断为严重OSA(p = 0.001)。在BMI,NC与AHI,唤醒指数,平均SpO2和去饱和指数之间发现正相关。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。OSA在我们的患者中非常普遍。此外,BMI和NC独立影响其疾病的严重程度。
更新日期:2020-10-02
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