Two new naphthyl-products calinaphthyltriol A (1) and calinaphthalenone A (2) were isolated from Aspergillus californicus IBT 16748 together with one known compound ophiobolin X (3). Their structures were elucidated by extensive spectroscopic analyses. The absolute configuration of 2 was solved by comparing its optical rotation with data for the known compounds 4, 5, and 6 as well as theoretical calculations. The antibacterial and cytotoxic activities of 1 and 3 were evaluated. Both compounds did not show antibacterial activity (MIC > 96 µg·ml⁻¹) against a few selected clinically relevant Gram positive and Gram negative bacterial strains. However, they showed moderate cytotoxicity against HL-60 cell line with IC₅₀ values of 18 and 24 µg·ml⁻¹, respectively.

从加州曲霉IBT 16748中分离得到两种新的萘基产物calinaphthyltriol A( 1 )和calinaphthalenone A( 2 )以及一种已知的化合物ophiobolin X( 3 )。通过广泛的光谱分析阐明了它们的结构。的绝对构型2是由它的旋光与用于已知化合物的数据进行比较来解决4，5，和6以及理论计算。评价了1和3的抗菌和细胞毒活性。两种化合物均未显示抗菌活性（MIC > 96 µg·ml ^-1) 对抗一些选定的临床相关革兰氏阳性和革兰氏阴性细菌菌株。然而，它们对HL-60 细胞系显示出中等的细胞毒性，IC ₅₀值分别为18 和24 µg·ml ^-1。