Abstract

Biosensors operating based on electrical methods are being accelerated toward rapid and efficient detection that improve the performance of the device. Continuous study in nano- and material-sciences has led to the inflection with properties of nanomaterials that fit the trend parallel to the biosensor evolution. Advancements in technology that focuses on nano-hybrid are being used to develop biosensors with better detection strategies. In this sense, titanium dioxide (TiO₂) nanomaterials have attracted extensive interest in the construction of electrical biosensors. The formation of TiO₂ nano-hybrid as an electrical transducing material has revealed good results with high performance. The modification of the sensing portion with a combination (nano-hybrid form) of nanomaterials has produced excellent sensors in terms of stability, reproducibility, and enhanced sensitivity. This review highlights recent research advancements with functional TiO₂ nano-hybrid materials, and their victorious story in the construction of electrical biosensors are discussed. Future research directions with commercialization of these devices and their extensive utilizations are also discussed.

摘要

基于电气方法运行的生物传感器正在加速向快速有效的检测方向发展，从而提高设备的性能。纳米和材料科学的持续研究导致纳米材料的特性发生变化，这些特性符合与生物传感器发展平行的趋势。专注于纳米混合的技术进步被用于开发具有更好检测策略的生物传感器。从这个意义上说，二氧化钛（TiO ₂）纳米材料在电子生物传感器的构建中引起了广泛的兴趣。TiO _2的形成纳米杂化材料作为电导材料已经显示出具有高性能的良好结果。用纳米材料的组合（纳米混合形式）对传感部分进行修改，在稳定性、再现性和增强的灵敏度方面产生了出色的传感器。_{这篇综述重点介绍了功能性 TiO 2}纳米混合材料的最新研究进展，并讨论了它们在构建电生物传感器方面的成功故事。还讨论了这些设备的商业化及其广泛应用的未来研究方向。