Trimethylamine‐N‐oxide (TMAO) is a potential indicator of cardiovascular disease and chronic kidney disorders. It is important to monitor the TMAO level in plasma or serum of hemodialysis patients. A simple liquid chromatography/differential ion mobility spectrometry tandem mass spectrometry (HPLC/DMS‐MS/MS) method was established and validated for the determination of TMAO in the serum of hemodialysis patients.

中文翻译：

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一种测定人血清中三甲胺-N-氧化物的简单液相色谱/差示离子迁移谱串联质谱法：在透析患者中​​的应用

三甲胺-N-氧化物（TMAO）是心血管疾病和慢性肾脏疾病的潜在指标。监测血液透析患者血浆或血清中的 TMAO 水平很重要。建立并验证了一种简单的液相色谱/差示离子迁移谱串联质谱 (HPLC/DMS-MS/MS) 方法，用于测定血液透析患者血清中的 TMAO。