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Thermodynamic assessment of therapeutic hypothermia techniques for rehabilitation of post-cardiac arrest patients
Case Studies in Thermal Engineering ( IF 6.4 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.csite.2020.100752
Ellen Cavalcante Alves , Carlos Eduardo Keutenedjian Mady

A comparative study of the three main methods for inducing hypothermia in post-cardiac arrest patients is performed. A human thermal model from the literature is adapted to simulate an average adult during treatment using intravascular cooling, extracorporeal cooling, or a combination of both. The investigation is carried out using the temperature profile that best represents the hypothalamus temperature, and uses the destroyed exergy as a quality index. Each of these techniques is modeled by an equation for the exergy efficiency. As a result of the better stability and control of the patient's core temperature, as well as a reduction of destroyed exergy, the model that makes use of both techniques simultaneously proves to be, from a thermodynamic perspective, superior to the others, although each has advantages and disadvantages.



中文翻译:

治疗性低温疗法对心脏骤停后患者康复的热力学评估

对心脏骤停后诱发体温过低的三种主要方法进行了比较研究。文献中的人体热模型适用于在使用血管内冷却,体外冷却或两者结合的治疗过程中模拟普通成年人。使用最能代表下丘脑温度的温度曲线进行研究,并将被破坏的火用作为质量指标。这些技术中的每一种都通过一个方程来模拟,以提高火用效率。由于更好的稳定性和对患者核心温度的控制,以及减少了被破坏的火用,因此从热力学角度来看,同时使用这两种技术的模型被证明优于其他技术,尽管每种技术都有的优点和缺点。

更新日期:2020-10-02
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