We report findings from a new survey of US public attitudes toward human-animal chimeric embryo (HACE) research, designed to compare with recently reported Japanese survey data. We find that 59% of the US public can personally accept the process of injecting human induced pluripotent stem cells into genetically modified swine embryos and having human tissues produced in a pig's body transplanted into a human. This is greater acceptance than in Japan, and there is even strong acceptance among those with strong religious affiliations and who self-identify as conservatives. We argue that strong public support for HACE research, as well as the emerging literature suggesting that humanization of research animals is very unlikely, should compel the NIH to lift its current moratorium on HACE research.

我们报告了一项关于美国公众对人-动物嵌合胚胎 (HACE) 研究态度的新调查的结果，旨在与最近报告的日本调查数据进行比较。我们发现，59%的美国公众可以个人接受将人类诱导的多能干细胞注入转基因猪胚胎，并将猪体内产生的人体组织移植到人体中的过程。这比日本的接受度更高，甚至在那些有强烈宗教信仰和自认为保守派的人中也有很强的接受度。我们认为，公众对 HACE 研究的大力支持，以及新出现的文献表明研究动物不太可能人源化，应该会迫使 NIH 取消目前对 HACE 研究的暂停。