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Understanding the potential of lactobacilli in recurrent UTI prevention
Microbial Pathogenesis ( IF 3.3 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.micpath.2020.104544
Stylianos Vagios 1 , Helai Hesham 1 , Caroline Mitchell 1
Affiliation  

Urinary tract infections (UTIs) are one of the most common infections in women. The only proven preventive strategy for recurrent UTIs is prophylactic antibiotics. Given growing antibiotic resistance, the use of probiotics has been proposed as an alternative to antibiotics. Herein, we discuss the current evidence to support the possibility that exogenous lactobacilli may limit the pathogenicity of uropathogens such as E. coli. Probiotics appear to have a significant potential in prevention of recurrent UTI, however, additional data are needed to understand how they can be effectively used in clinical practice.



中文翻译:

了解乳酸菌在复发性UTI预防中的潜力

尿路感染(UTIs)是女性最常见的感染之一。公认的复发性尿路感染的预防策略是预防性抗生素。鉴于对抗生素的抵抗力不断增强,已提出使用益生菌替代抗生素。在这里,我们讨论了当前的证据,以支持外源性乳酸菌可能会限制尿路致病菌(如大肠杆菌)的致病性的可能性。益生菌似乎具有预防复发性UTI的巨大潜力,但是,还需要更多数据来了解如何在临床实践中有效使用它们。

更新日期:2020-10-02
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