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Intestinal Myxoid Leiomyosarcoma in a Sambar Deer (Rusa unicolor)
Journal of Comparative Pathology ( IF 0.8 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.jcpa.2020.08.008
Fábio S Mendonça 1 , Givaldo B Silva Filho 1 , Hisadora A C Bom 1 , Silvio M C Fonseca 1 , Marcio A Silva 2 , Luciana C Rameh-de-Albuquerque 2 , Julian Beingesser 3 , Francisco A Uzal 3
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A 9-year-old male sambar deer (Rusa unicolor) that died during sedation had a large and firm polypoid mass, which expanded the small intestinal wall and partially obstructed the duodenal lumen. Histopathology revealed a pleomorphic sarcoma composed of stellate to spindloid cells loosely arranged in an abundant myxoid matrix. The cytoplasm of the neoplastic cells was strongly immunopositive for vimentin and smooth muscle actin, but negative for c-KIT, desmin and myoglobin. The findings are consistent with intestinal myxoid leiomyosarcoma, which is rare in cervids and has not been described in the sambar deer, which is an endangered species.



中文翻译:

水鹿的肠道粘液样平滑肌肉瘤(Rusa unicolor)

一头在镇静期间死亡的9岁雄性水鹿(Rusa unicolor)有一个大而坚硬的息肉状肿块,使小肠壁扩张并部分阻塞十二指肠腔。组织病理学显示多形性肉瘤,由星状至纺锤体细胞组成,松散排列在丰富的粘液样基质中。肿瘤细胞的细胞质对波形蛋白和平滑肌肌动蛋白呈强免疫阳性,但对 c-KIT、结蛋白和肌红蛋白呈阴性。研究结果与肠道粘液样平滑肌肉瘤一致,后者在鹿科动物中很少见,在濒危物种水鹿中未见报道。

更新日期:2020-10-02
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