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Balancing Expectations for Success in Stem Cell-Based Clinical Trials for Parkinson’s Disease
Cell Stem Cell ( IF 19.8 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.stem.2020.09.002 Olle Lindvall
中文翻译:
在基于干细胞的帕金森氏病临床试验中取得成功的平衡期望
更新日期:2020-10-02
Cell Stem Cell ( IF 19.8 ) Pub Date : 2020-10-01 , DOI: 10.1016/j.stem.2020.09.002 Olle Lindvall
Upcoming clinical trials assessing transplantation of stem cell-derived dopaminergic neurons into the striatum in patients with Parkinson’s disease could generate groundbreaking results on neuronal replacement in the human brain. However, as highlighted here, the road toward a clinically competitive treatment for this multisystem disorder will probably be long and winding.
中文翻译:
在基于干细胞的帕金森氏病临床试验中取得成功的平衡期望
即将进行的评估帕金森氏病患者的干细胞来源的多巴胺能神经元移植到纹状体中的临床试验可能在人脑神经元置换方面产生突破性的结果。但是,正如此处强调的那样,针对这种多系统疾病的临床竞争性治疗之路可能会很长且曲折。