Studies on the anaerobic bacteria Porphyromonas, mainly focused on P. gingivalis, have revealed new bacterial structures, metabolic pathways, and physiologic functionalities. Porphyromonas are mainly described as being associated with mammals and involved in chronic oral infections and secondary pathologies such as cancers or neurodegenerative diseases. In this review, we collected and analyzed information regarding Porphyromonas isolation sites and associated conditions and showed that Porphyromonas are detected in numerous pristine and anthropic environments and that their host range appears wider than previously believed, including aquatic animals, arthropods, and birds, even if their predominant hosts remain humans, pets, and farm animals. Our analyses also revealed their presence in multiple organs and in a substantial proportion of healthy contexts. Overall, the growing numbers of microbiota studies have allowed unprecedented advances in the understanding of Porphyromonas ecology but raise questions regarding their phylogenic assignment. In conclusion, this systematic and meta-analysis provides an overview of current knowledge regarding Porphyromonas ecological distribution and encourages additional research to fill the knowledge gaps to better understand their environmental distribution and inter- and intra-species transmission.

对厌氧细菌卟啉单胞菌的研究，主要集中在牙龈卟啉单胞菌上，揭示了新的细菌结构、代谢途径和生理功能。卟啉单胞菌主要被描述为与哺乳动物有关，并参与慢性口腔感染和继发性病变，如癌症或神经退行性疾病。在这篇综述中，我们收集并分析了关于卟啉单胞菌分离位点和相关条件的信息，并表明卟啉单胞菌在许多原始和人类环境中检测到它们的宿主范围似乎比以前认为的更广泛，包括水生动物、节肢动物和鸟类，即使它们的主要宿主仍然是人类、宠物和农场动物。我们的分析还揭示了它们存在于多个器官和大部分健康环境中。总体而言，越来越多的微生物群研究使得对卟啉单胞菌生态学的理解取得了前所未有的进展，但也提出了关于它们的系统发育分配的问题。总之，这项系统的荟萃分析概述了目前关于卟啉单胞菌的知识 生态分布并鼓励进行更多研究以填补知识空白，以更好地了解其环境分布以及物种间和物种内的传播。