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The pharmacological potential of catechin
Indian Journal of Biochemistry and Biophysics ( IF 1.5 ) Pub Date : 2020-09-30
Aditya Ganeshpurkar, Ajay Saluja

The contemporary scientific community has presently recognized flavonoids to be a unique class of therapeutic molecules due to their diverse therapeutic properties. Of these, catechin, also, has been explored for a number of pharmacological effects. The present review aims to document the therapeutic potential of catechin. Tea leave, catechu, and much more possess catechin as one of the active constituents. Today, catechin has been observed for its nutraceutical effect. The objective of this review is to examine the evidence of the effectiveness and pharmacological effects of catechin. Preclinical, as well as randomized controlled clinical trials pertaining to studies of catechin,are included in the study. Chemical properties of catechin and its structure-activity relationship about various biological activities have also been documented. The review revealed protective effects of catechin on functions and integrity of liver, kidney, heart , and age-related memory impairment. Catechin demonstrated the antimicrobial, anticancer, antihypertensive, anticoagulant , and antiulcer effect. The present review highlights the current information and the health-promoting effects of catechin. Along with this, the chemotherapeutic potential of the same has also been discussed.

中文翻译:

儿茶素的药理潜力

由于其多样化的治疗特性,当代科学界目前已将类黄酮视为一类独特的治疗分子。其中,儿茶素还被研究具有多种药理作用。本综述旨在证明儿茶素的治疗潜力。茶叶,儿茶和许多其他成分都将儿茶素作为有效成分之一。如今,已观察到儿茶素的保健功效。这篇综述的目的是检查儿茶素的有效性和药理作用的证据。与儿茶素研究有关的临床前以及随机对照临床试验也包括在研究中。儿茶素的化学性质及其与各种生物活性的构效关系也已有文献记载。该评价揭示了儿茶素对肝,肾,心脏和与年龄相关的记忆障碍的功能和完整性的保护作用。儿茶素具有抗微生物,抗癌,抗高血压,抗凝血和抗溃疡的作用。本综述重点介绍了儿茶素的最新信息和促进健康的作用。同时,还讨论了其化学治疗潜力。
更新日期:2020-09-30
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