Abstract Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on “Meet the Press” that “[T]he U.S. needs a ‘breakthrough’ in coronavirus testing to help screen Americans and get a more accurate picture of the virus’ spread.” We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper.

中文翻译：

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一种检测 COVID-19 抗体和病毒颗粒的光纤-纳米光子方法

摘要 白宫冠状病毒特别工作组协调员黛博拉·伯克斯博士在“会见媒体”节目中告诉 NBC 新闻，“美国需要在冠状病毒检测方面取得‘突破’，以帮助筛查美国人并更准确地了解病毒传播。” 自 2001 年炭疽袭击以来，我们一直参与生物病原体检测，并且是第一个实时检测炭疽的公司。我们为快速检测炭疽而开发的激光光谱技术的变体可用于检测严重急性呼吸系统综合症冠状病毒 2（SARS-CoV-2 病毒）。除了检测单个病毒外，该技术还允许我们读取其表面蛋白质结构。特别是，我们一直在基于各种量子光学方法进行研究，旨在提高我们检测 Corona Virus Disease-2019 (COVID-19) 病毒感染的能力。事实上，在感染过去后检测小浓度抗体是一个具有挑战性的问题。同样，疾病的早期检测，甚至在可检测的抗体群建立之前，也非常重要。我们的团队正在研究这个问题的两个方面。写这篇论文是为了激发物理和生物科学家对这个重要问题的兴趣。因此，它是作为教程（评论）和未来工作（预览）的组合而编写的。我们与 Federico Capasso 教授和编辑 Dennis Couwenberg 一起向所有在 COVID-19 问题的各个方面如此英勇工作的人表示感谢。我们感谢博士。Capasso 和 Couwenberg 受邀撰写本文。